Results 91 to 100 of about 2,064,106 (289)
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Ground state solutions for a quasilinear Kirchhoff type equation
Electronic Journal of Qualitative Theory of Differential Equations, 2016 We study the ground state solutions of the following quasilinear Kirchhoff type equation \[ -\left(1+b\int_{\mathbb{R}^{3}}|\nabla u|^2dx\right)\Delta u + V(x)u-[\Delta(u^2)]u=|u|^{10}u+\mu |u|^{p-1}u,\qquad x\in \mathbb{R}^3, \] where $b\geq 0$ and $\mu$
Hongliang Liu, Haibo Chen, Qizhen Xiao
doaj +1 more source
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
Eigenlevel statistics of the quantum adiabatic algorithm
, 2005 We study the eigenlevel spectrum of quantum adiabatic algorithm for 3-satisfiability problem, focusing on single-solution instances. The properties of the ground state and the associated gap, crucial for determining the running time of the algorithm, are
A. M. Childs +6 more
core +1 more source
Ground state solutions for singular quasilinear elliptic equations
, 2010 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Yang, Zuodong, Yu, Chuanwei
openaire +2 more sources
Ground state solutions for some indefinite variational problems
Journal of Functional Analysis, 2009 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Szulkin, Andrzej, Weth, Tobias
openaire +1 more source
Ground state solutions for Schrödinger-Born-Infeld equations
Matemática Contemporânea, 2022 Summary: In this note we revise the arguments used to find ground states solutions for an elliptic system which envolves the Schrödinger equation coupled with the electrostatic equation of the Born-Infeld electromagnetic theory. The main difficulties are related to the second equation of the system which is nonlinear.
openaire +2 more sources
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Minimal mass blow-up solutions for the $L^2$ critical NLS with inverse-square potential
, 2018 We study minimal mass blow-up solutions of the focusing $L^2$ critical nonlinear Schr\"odinger equation with inverse-square potential, \[ i\partial_t u + \Delta u + \frac{c}{|x|^2}u+|u|^{\frac{4}{N}}u = 0, \] with $N\geqslant 3$ and ...
Csobo, Elek, Genoud, François
core +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source