Results 101 to 110 of about 2,064,106 (289)

Theoretical Proof of and Proposed Experimental Search for the Ground Triplet State of a Wigner-Regime Two-Electron ‘Artificial Atom’ in a Magnetic Field

Axioms
It is experimentally established that there is no ground triplet state of the natural He atom. There is also no exact analytical solution to the Schrödinger equation corresponding to this state.
Marlina Slamet, Viraht Sahni
doaj   +1 more source

Spin- and charge-density waves in the Hartree-Fock ground state of the two-dimensional Hubbard model

, 2011
The ground states of the two-dimensional repulsive Hubbard model are studied within the unrestricted Hartree-Fock (UHF) theory. Magnetic and charge properties are determined by systematic, large-scale, exact numerical calculations, and quantified as a ...
Anderson P W, Capone M, Chang C, Chang C, Chia-Chen Chang, Eric J Walter, Igoshev P A, Jie Xu, Maier T A, Martin R M, Montorsi A, Overhauser A W, Penn D R, Rasetti M, Schulz H J, Shiwei Zhang, Sénéchal D, Zhang S, Zhang S   +18 more
core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Ground state sign-changing solution for a logarithmic Kirchhoff-type equation in $\mathbb{R}^{3}$

Electronic Journal of Qualitative Theory of Differential Equations
We investigate the following logarithmic Kirchhoff-type equation: \begin{equation*} \left(a+b\int_{\mathbb{R}^{3}}|\nabla u|^{2}+V(x)u^{2}dx\right)[-\Delta u+V(x)u]=|u|^{p-2}u\ln |u|,\qquad x\in\mathbb{R}^{3}, \end{equation*} where $a,b>0$ are constants,
Wei-Long Yang, Jia-Feng Liao
doaj   +1 more source

Existence of Positive Ground State Solution for the Nonlinear Schrödinger-Poisson System with Potentials

Advances in Mathematical Physics, 2018
In the present paper we study the existence of positive ground state solutions for the nonautonomous Schrödinger-Poisson system with competing potentials. Under some assumptions for the potentials we prove the existence of positive ground state solution.
Lu Xiao, Haiqin Qian, Mengmeng Qu, Jun Wang   +3 more
doaj   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Existence of a ground-state solution for a quasilinear Schrödinger system

Frontiers in Physics
In this paper, we consider the following quasilinear Schrödinger system.−Δu+u+k2Δ|u|2u=2αα+β|u|α−2u|v|β,x∈RN,−Δv+v+k2Δ|v|2v=2βα+β|u|α|v|β−2v,x∈RN,where k < 0 is a real constant, α > 1, β > 1, and α + β < 2*.
Xue Zhang, Jing Zhang, Jing Zhang, Jing Zhang   +3 more
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Structure of ground state solutions for singular elliptic equations with a quadratic gradient term

Electronic Journal of Differential Equations, 2011
We establish results on existence, non-existence, and asymptotic behavior of ground state solutions for the singular nonlinear elliptic problem $$displaylines{ -Delta u = g(u)| abla u |^2 + lambdapsi(x) f(u) quadhbox{in } mathbb{R}^N,\ u > 0 ...
Antonio Luiz Melo, Carlos Alberto Santos
doaj  

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source