Results 101 to 110 of about 249,335 (265)

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Existence of ground state solutions for quasilinear Schrodinger equations with variable potentials and almost necessary nonlinearities

Electronic Journal of Differential Equations, 2018
In this article we prove the existence of ground state solutions for the quasilinear Schrodinger equation $$ -\Delta u+V(x)u-\Delta (u^2)u= g(u), \quad x\in \mathbb{R}^N, $$ where $N\ge 3$, $V\in \mathcal{C}^1(\mathbb{R}^N, [0, \infty))$ satisfies ...
Sitong Chen, Xianhua Tang
doaj  

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Ground state solutions for singular quasilinear elliptic equations

, 2010
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Yang, Zuodong, Yu, Chuanwei
openaire   +2 more sources

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Solution-synthesized stable triaza[4]triangulene triradical with a quartet ground state

Nature Communications
As a renowned class of open-shell molecules characterized by triangular nanographenic structures and novel magnetic properties with high-spin ground states, triangulenes are attractive targets to both synthetic chemists and molecular magnet researchers ...
Xudong Bai, Di Zhang, Yushuang Zhang, Yihan Wang, Yanning Cheng, Yi Xie, Ziqi Zhu, Shang-Da Jiang, Dahui Zhao   +8 more
doaj   +1 more source

Antiferromagnetic sawtooth chain with Heisenberg and Ising bonds

Condensed Matter Physics, 2009
The sawtooth chain with pairs of S=1/2 spins interacting with XXZ-interactions placed on each second tooth is considered. All other interaction bonds are taken to be of Ising type.
V. Ohanyan
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Existence of ground state solution for critical N-Laplacian Kirchhoff-type problem with convolution nonlinearity

Bulletin of Mathematical Sciences
In this paper, we investigate the following N-Laplacian Kirchhoff–Choquard-type equation involving the critical exponential growth nonlinearity of Trudinger–Moser-type: −1+b∫ℝN|∇u|NdxΔNu+V(x)|u|N−2u=(|x|−μ∗F(x,u))f(x,u),x∈ℝN,N≥2,u∈W1,N(ℝN), where ...
Lizhen Lai, Dongdong Qin, Die Hu, Jing Zhang   +3 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source