Results 111 to 120 of about 21,392,187 (250)

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Solution-synthesized stable triaza[4]triangulene triradical with a quartet ground state

Nature Communications
As a renowned class of open-shell molecules characterized by triangular nanographenic structures and novel magnetic properties with high-spin ground states, triangulenes are attractive targets to both synthetic chemists and molecular magnet researchers ...
Xudong Bai, Di Zhang, Yushuang Zhang, Yihan Wang, Yanning Cheng, Yi Xie, Ziqi Zhu, Shang-Da Jiang, Dahui Zhao   +8 more
doaj   +1 more source

Antiferromagnetic sawtooth chain with Heisenberg and Ising bonds

Condensed Matter Physics, 2009
The sawtooth chain with pairs of S=1/2 spins interacting with XXZ-interactions placed on each second tooth is considered. All other interaction bonds are taken to be of Ising type.
V. Ohanyan
doaj   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

New electronic state documents list - January 2024

The monthly New South Carolina State Documents publication by the State Library provides a list of state documents published by state agencies that have been cataloged and added to the South Carolina State Documents Depository.
South Carolina State Library
core  

Positive ground state solutions for quasicritical Klein-Gordon-Maxwell type systems with potential vanishing at infinity

Electronic Journal of Differential Equations, 2017
This article concerns the Klein-Gordon-Maxwell type system when the nonlinearity has a quasicritical growth at infinity, involving zero mass potential, that is, $V(x)\to 0$, as $|x|\to\infty$.
Elson Leal de Moura, Olimpio H. Miyagaki, Ricardo Ruviaro   +2 more
doaj  

Existence of ground state solution for critical N-Laplacian Kirchhoff-type problem with convolution nonlinearity

Bulletin of Mathematical Sciences
In this paper, we investigate the following N-Laplacian Kirchhoff–Choquard-type equation involving the critical exponential growth nonlinearity of Trudinger–Moser-type: −1+b∫ℝN|∇u|NdxΔNu+V(x)|u|N−2u=(|x|−μ∗F(x,u))f(x,u),x∈ℝN,N≥2,u∈W1,N(ℝN), where ...
Lizhen Lai, Dongdong Qin, Die Hu, Jing Zhang   +3 more
doaj   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

Molecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

New electronic state documents list -February 2024

The monthly New South Carolina State Documents publication by the State Library provides a list of state documents published by state agencies that have been cataloged and added to the South Carolina State Documents Depository.
South Carolina State Library
core  

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source