Results 131 to 140 of about 6,855 (245)

TrxR2 Lactylation Facilitates Mitochondrial Protection and Endothelial Ferroptosis Resistance in Diabetic Cardiomyopathy

open access: yesAdvanced Science, EarlyView.
TrxR2 deletion in diabetic mice suppresses TUFM‐AMPK‐FUNDC1‐dependent mitophagy in endothelial cells, resulting in SCP2 upregulation and mitochondrial translocation of ACSL4. Mitochondrial ACSL4 promotes mitochondrial eicosanoid biosynthesis and ferroptosis, thereby aggravating cardiac microvascular injury and diabetic cardiomyopathy.
Su Li   +16 more
wiley   +1 more source

Long-term deformation of coastal volcanoes in SE-Asia: linking displacement rates, volcanic activity and flank instabilities. [PDF]

open access: yesBull Volcanol
Zorn EU   +7 more
europepmc   +1 more source

Influence of Hydrogen‐Incorporation on the Bulk Electronic Structure and Chemical Bonding in Palladium

open access: yesAdvanced Science, EarlyView.
Hydrogen incorporation in palladium is directly probed using in situ ambient‐pressure hard X‐ray photoelectron spectroscopy under realistic, application‐relevant conditions. Correlated structural, spectroscopic, and theoretical analysis reveals how hydrogen loading modifies structure, electronic structure, and metal‐hydrogen bonding, resolving long ...
Lars J. Bannenberg   +8 more
wiley   +1 more source

Study on non-tectonic gravity effects in western Shandong. [PDF]

open access: yesSci Rep
Li S   +6 more
europepmc   +1 more source

Integrating Human Intestinal Organoids into FDA'S New Approach Methodologies for Drug Discovery

open access: yesAdvanced Science, EarlyView.
Illustration summarizes how human intestinal organoids (HIOs) are becoming transformative in preclinical research. Preclinical drug discovery pipelines often rely on animal models for ADMET studies, even though interspecies ADME gaps, poor external validity, and high attrition rates are common.
Debarun Patra   +6 more
wiley   +1 more source

Prognostication of Remote Sensing for Karst Heat Corrosion Subsidence of the Whole Urban Ground of Guilin

open access: bronze, 2002
吴虹   +6 more
openalex   +2 more sources

Smart Optogenetics for Real‐Time Automated Control of Cardiac Electrical Activity

open access: yesAdvanced Science, EarlyView.
We are able to stop dangerous heart‐rhythm spirals before they fully form. Within about 100 ms, it pinpoints the spiral's tiny central tip (≈0.9 mm) using light‐based sensing and machine learning, then shines targeted light to shut it down. This fast, precise, closed‐loop approach detects, targets, and terminates arrhythmias in real time.
Shanliang Deng   +15 more
wiley   +1 more source

Home - About - Disclaimer - Privacy