Results 71 to 80 of about 1,270,932 (284)
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
Remote SensingRecent advancements in artificial intelligence (AI) and deep learning enable more accurate, scalable, and automated mapping. This paper provides a comprehensive review of the applications of AI, particularly deep learning, in landslide inventory mapping.
Xiao Chen +4 more
doaj +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Cyber-Deception and Attribution in Capture-the-Flag Exercises
, 2015 Attributing the culprit of a cyber-attack is widely considered one of the major technical and policy challenges of cyber-security. The lack of ground truth for an individual responsible for a given attack has limited previous studies.
Kulkarni, Nimish +4 more
core +1 more source
Why human connection is the true metric of research success
FEBS Open Bio, EarlyView.Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
wiley +1 more source
Motion robust 4D-MRI sorting based on anatomic feature matching: A digital phantom simulation study
Radiation Medicine and Protection, 2020 Purpose: Motion artifacts induced by breathing variations are common in 4D-MRI images. This study aims to reduce the motion artifacts by developing a novel, robust 4D-MRI sorting method based on anatomic feature matching and applicable in both cine and ...
Zi Yang +4 more
doaj +1 more source
FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
Applications of Saturn/Apollo automated data system capabilities to problems and environmental impacts of urban transportation [PDF]
The work plan to achieve the objectives of this project is presented. Tasks discussed include ground truth, remotely sensed data, and the correlation of ground truth and the remotely sensed ...
Saussy, G. A.
core +1 more source
Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Aging and Cancer, EarlyView.Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source
Some notes on social science research related to legislative drafting [PDF]
, 1993 Notes on the relationship between social behavior and legislation, and how to ground draft legislation in 'truth learned from facts' to better influence social ...
Seidman, Ann, Seidman, Robert B.
core