Results 81 to 90 of about 485,769 (266)

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

open access: yesFEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer   +7 more
wiley   +1 more source

Experiences with Ground Water on Construction

open access: yesJournal of the Soil Mechanics and Foundations Division, 1962
Unusual Canadian examples presented include control of groundwater at Steep Rock Iron Mines by trapping it before it reached drained lake bed; La Tuque hydroelectric development where seepage around large concrete dam showed itself in small natural lake, and Aguasabon hydroelectric development, where perched reservoir was used as main forebay in area ...
openaire   +3 more sources

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

open access: yesFEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey   +4 more
wiley   +1 more source

Recent insights into the molecular mechanism of ubiquinol oxidation by cytochrome bc1

open access: yesFEBS Open Bio, EarlyView.
The review reflects on the mechanism of the catalytic reaction in cytochrome bc1: the electron bifurcation that involves the separation of two electrons derived from the quinol oxidation to opposite sides of the enzyme across the membrane. This review summarizes the long‐standing effort to understand the mechanism of quinol oxidation catalyzed by ...
Anna Wójcik‐Augustyn   +2 more
wiley   +1 more source

Spatial assessment of heavy metal contamination in groundwater in the Kadaladi region, Tamil Nadu, India

open access: yesScientific Reports
Groundwater quality in Kadaladi is a critical concern due to contamination from natural and human activities. This study assesses heavy metal concentrations across pre-monsoon and post-monsoon seasons at 44 sampling sites, using the Heavy Metal Pollution
M. Seeththa Sankar Narayanan   +5 more
doaj   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

open access: yesFEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao   +10 more
wiley   +1 more source

Delineation of palaeochannels using DEM and spectral indices in the Gundar basin of Kadaladi region

open access: yesScientific Reports
The identification and mapping of palaeochannels offer an essential understanding of past fluvial processes and groundwater potential, particularly in arid and semi-arid regions facing severe water stress.
M. Seeththa Sankar Narayanan   +5 more
doaj   +1 more source

Ionic composition of snow cover on the territory of Siberia and the Far East

open access: yesЛëд и снег
Long-term (from 2007 to 2022) observations of the dynamics of acidity, mineralization and ionic composition of snow cover in remote mountainous and lowland landscapes of Northern Asia were carried out.
A. V. Saltykov   +3 more
doaj   +1 more source

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