Results 231 to 240 of about 1,132,405 (294)

Diffusion‐Based Generative Model With Scaffold‐Hopping Strategy Yields Highly Potent Bioactive Molecules

Advanced Science, EarlyView.
SMarT‐Diff introduces a multi‐objective generative paradigm that integrates scaffold hopping with structure‐aware scoring to enable controlled exploration beyond the training distribution. The framework consistently balances drug‐likeness, synthesizes accessibility and bioactivity, yielding chemically diverse candidates with enhanced properties.
Yuwei Yang, Xiaoqing Gong, Shukai Gu, Jing Li, Bo Liu, Yanan Tian, Qianqian Zhang, Xiaojun Yao, Huanxiang Liu   +8 more
wiley   +1 more source

The mitochondrial genome of <i>Palpimanus capensis</i> Simon, 1893 (Araneae, Palpimanidae) from ultraconserved elements (UCEs). [PDF]

Mitochondrial DNA B Resour
Merrill CM, Patrick LB, Wood HM, Santos SR.   +3 more
europepmc   +1 more source

Sulfated Cyclocarya Paliurus Polysaccharide Sorchestrates the Gut Microbiome to Mobilize a Host‐Derived 12‐HEPE Against Ulcerative Colitis

Advanced Science, EarlyView.
A sulfated polysaccharide (SCP) from Cyclocarya paliurus alleviates ulcerative colitis by reshaping the gut microbiome. This remodeled microbiota orchestrates the upregulation of the host‐derived lipid 12‐HEPE, which directly inhibits the TLR4/NF‐κB pathway to suppress inflammation.
Xianxiang Chen, Mingyue Shen, Rui Zhang, Zhibing Huang, Hui Niu, Qiang Yu, Yi Chen, Xiangwen Pan, Liyuan Rong, Huiliang Wen, Jun Yang, Jianhua Xie   +11 more
wiley   +1 more source

Effects of Wood Biomass Combustion Residues on the Structure, Diversity, and Trophic Functions of Soil Fungi. [PDF]

Int J Mol Sci
Wyszkowska J, Boros-Lajszner E, Baćmaga M, Kucharski J.   +3 more
europepmc   +1 more source

Tailoring Multifunctional Carbon Dots via Precursor Stoichiometry: Switching Between Solid‐State Fluorescence and Broadband Absorption Through Aggregation Control

Advanced Science, EarlyView.
Precursor stoichiometry programs the surface chemistry of carbon dots, directing their self‐assembly into distinct aggregation modes. Aldehyde‐enriched surfaces form ordered, hydrogen‐bonded assemblies that enable bright red solid‐state fluorescence, whereas amine‐rich surfaces promote compact π–π stacked aggregates with broadband visible‐light ...
Gaixia Yang, Hao Sun, Defa Hou, Fulin Yang, Yuan Zou, Bei Zhou, Lanxiang Liu, Xu Lin, Guanben Du   +8 more
wiley   +1 more source

Habitat filtering, not dispersal limitation, drives ant and termite community assembly along a tropical forest regeneration gradient. [PDF]

Oecologia
Grella N, Donoso DA, Müller J, Falconí-López A, Busse A, Kriegel P, Püls M, Rabl D, Seibold S, Feldhaar H.   +9 more
europepmc   +1 more source

Flexible Thin‐Film Heater Composed of Laser‐Induced Graphene and Poly(D, L‐Lactic Acid) with Electro‐ and Photo‐Thermal Properties toward Cancer Thermotherapy

Advanced Electronic Materials, EarlyView.
This study introduces a thin‐film‐type heat‐generating device that uses laser induced graphene (LIG) on a poly(D, L‐lactic) acid film, which realizes both resistance heating by direct current application and photothermal conversion heating by near‐infrared light irradiation.
Masato Saito, Sota Harada, Ran Imai, Kon Son, Toshinori Fujie   +4 more
wiley   +1 more source

Tropical Montane Cloud Forests Have High Resilience to Five Years of Severe Soil Drought. [PDF]

Glob Chang Biol
Bartholomew DC, Bittencourt PRL, Galiano Cabrera D, Sacatuma Cruz R, Chambi Paucar JR, Corrales Alvarez D, Cosio E, Espinoza Otazu B, Mamani DM, Meir P, Muñoz Hermoza GA, Oliveira RS, Puma Vilca BL, Rosalai A, Salas Yupayccana C, Salinas N, Sanchez Tintaya J, Yuca Palomino JA, Metcalfe DB.   +18 more
europepmc   +1 more source

Integrating Automated Electrochemistry and High‐Throughput Characterization with Machine Learning to Explore Si─Ge─Sn Thin‐Film Lithium Battery Anodes

Advanced Energy Materials, Volume 15, Issue 11, March 18, 2025.
A closed‐loop, data‐driven approach facilitates the exploration of high‐performance Si─Ge─Sn alloys as promising fast‐charging battery anodes. Autonomous electrochemical experimentation using a scanning droplet cell is combined with real‐time optimization to efficiently navigate composition space.
Alexey Sanin, Jackson K. Flowers, Tobias H. Piotrowiak, Frederic Felsen, Leon Merker, Alfred Ludwig, Dominic Bresser, Helge Sören Stein   +7 more
wiley   +1 more source

Nonpyrogenic "Black" Nitrogen Likely Plays a Major Yet Underrecognized Role in the Global Nitrogen Cycle. [PDF]

Environ Sci Technol
Dos Santos JV, Goranov AI, Lambert KM, da Rosa Salles T, Carter SJ, Pearson A, Hatcher PG.   +6 more
europepmc   +1 more source