Results 31 to 40 of about 8,637 (216)

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Мathematical Simulation of Electromagnetic Parameters of Single Infinite Long Grounding Electrodes at Flowing of Alternating Power Current

Известия высших учебных заведений и энергетических объединенний СНГ: Энергетика, 2010
The paper presents results of a mathematical simulation of electromagnetic parameters of single lengthy grounding electrodes (electrode rod resistance, resistance against grounding alternating current flowing in the ground and grounding electrode voltage)
D. A. Gerasimovich, E. A. Dziaruhina
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Effect of grounding grid of power transmission line on buried pipeline under short circuit fault

You-qi chuyun, 2021
In order to study the electromagnetic interference of the short-circuit current of grounding point when power transmission line is in fault operation, a model for grounding grid of transmission line towers and buried pipelines was established with the ...
Shaojie WANG, Yuanchao HU, Wenlong ZHAO, Xun LI, Dong JING   +4 more
doaj   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Impact of Corrosion on Performance of Grounding Conductors in Urban Rail Transit Lines

Chengshi guidao jiaotong yanjiu
ObjectiveThe grounding devices of the traction power supply system in urban rail transit play a crucial role in ensuring the normal operation of equipment and personal safety.
Peng ZHONG, Yun LONG, Qiang WANG, Zining XIE, Ruicheng XU, Hongbo CHENG   +5 more
doaj   +1 more source

Simulation Study on Lightning Impulse Characteristics of Flexible Graphite Composite Grounding Materials Applied to Grounding Grid of Power System

Frontiers in Energy Research, 2022
The flexible graphite composite grounding electrode is a non-metallic grounding electrode with good electrical conductivity, corrosion resistance and non-ferromagnetic properties.
Yuanchao Hu, Tao Huang, Yunzhu An, Jianyuan Feng, Meng Cheng, Hongping Xie, Wentao Shen, Changqing Du   +7 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source