Results 91 to 100 of about 31,817,874 (257)

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

What works for whom in school-based anti-bullying interventions? An individual participant data meta-analysis

, 2023
: The prevalence of bullying worldwide is high (UNESCO, 2018). Over the past decades, many anti-bullying interventions have been developed to remediate this problem.
Kuijper, Steven C., Hensums, Maud, BIRC: the anti-Bullying Interventions Research Consortium, Overbeek, Geertjan, de Mooij, Brechtje, Fekkes, Minne, DeSmet, Ann   +6 more
core  

Antea Group Archeologie 2019/200

, 2020
In opdracht van J.A. Rodenburg B.V. heeft Antea Group in november 2019 een archeologisch booronderzoek uitgevoerd op een perceel nabij de Denariusstraat 19 te Oosterhout.
Koopmanschap, Dr. H.J.L.C. (Antea Group), Sophie, Drs. G. (Antea Group), Colijn, MA J.E. (Antea Group), Sophie, Drs. G (Antea Group)   +3 more
core   +1 more source

A comparative study of the effectiveness of Non-computer and Computer-based Cognitive Rehabilitation Interventions on Auditory/Visual Working Memory of Stroke Patients [PDF]

مجله پزشکی دانشگاه علوم پزشکی تبریز
Background. Given the fact that there is contradictory evidence regarding the effectiveness of computerized cognitive rehabilitation interventions, the present study intended to compare the potential effects of non-computer and computer-based cognitive ...
Marziyeh Alivandi Vafa, Behzad Shalchi, Mehdi Farhodi, Mohamad Ali Nazari, Leyla Abidi Horolar   +4 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Active group-based performing arts interventions in Parkinson’s disease: an updated systematic review and meta-analysis

BMJ Open
Objectives To assess the evidence for active group-based performing arts interventions for people with Parkinson’s disease (PD).Setting Scholarly literature (published in English) from any country or countries (last search February 2025). This systematic
Maxwell S Barnish, Rebecca V Nelson-Horne, Sarah E Reynolds   +2 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Antea Group Archeologie 2018/153

, 2016
In september 2018 heeft Antea Group in opdracht van CroonenBuro5 een archeologisch booronderzoek (verkennende fase) uitgevoerd voor een plangebied dat valt binnen het grotere bestemmingsplan Slotjes te Oosterhout. Het plangebied bestaat uit verschillende
Arkema, Drs. M. (Antea Group), Teekens, Drs. P. (Antea Group), Riddersma, F.S. (Antea Group), Researcher, Fens, Drs. R.L. (Antea Group), Researcher, Fens, MA R.L. (Antea Group), Researcher, Fens, R.L. (Antea Group), Researcher, Teekens, P.C. (Antea Group), Researcher, Fens, MA RL (Antea Group), Fens, Drs. R. (Antea Group), Fens, R.L. (Antea Group), ProjectMember, Looveren, V Van (Antea Group), Fens, MA R.L. (Antea Group), Editor, Fens, MA R.L. (Antea Group), Fens, drs. RL (Antea Group), Pels-Ouweneel, Drs. A. (Antea Group), Sophie, Drs. G. (Antea Group), Colijn, MA J.E. (Antea Group), Fens, drs. R.L. (Antea Group), Munster, Drs. B. van (Antea Group), La Fèber, drs. D.J. (Antea Group), Fens, R. (Antea Group), Researcher, Nater, MA C.I. (Antea Group), Dasselaar, MA M. van (Antea Group), Fèber, D. la (Antea Group), Nater, MSC C.I. (Antea Group), Looveren, Drs. V. van (Antea Group), Fens, MA R. (Antea Group), Arkema, MA M. (Antea Group), Fèber, Drs. D. la (Antea Group), Fens, drs RL (Antea Group), Tolsma, drs. J. (Antea Group), Riddersma, F. (Antea Group), Researcher, Veen, V van der (Antea Group), Vossen, Drs. I. (Antea Group), Teekens, Drs. P.C. (Antea Group), Colijn, J.E. (Antea Group), Sophie, drs. G.J.A. (Antea Group), Bostelen, Drs. T. van (Antea Group), Fens, R.L. (Antea Group), RelatedPerson, Arkema, M.H. (Antea Group), Akkerman, E. (Antea Group), Fèber, drs D.J. la (Antea Group), Looveren, MA V. van (Antea Group), Fèber, drs. D.J. la (Antea Group), Sophie, MA G. (Antea Group), Craane, Dr. M.L. (Antea Group)   +45 more
core   +1 more source

Why are health care interventions delivered over the internet? : a systematic review of the published literature [PDF]

, 2006
Background: As Internet use grows, health interventions are increasingly being delivered online. Pioneering researchers are using the networking potential of the Internet, and several of them have evaluated these interventions. Objective: The objective
Lindenmeyer, Antje, Powell, John, Thorogood, Margaret, Lindenmeyer, A, Powell, J, Lowe, P, Griffiths, F, Thorogood, M, Lowe, Pam, Griffths, Frances, Griffiths, Frances, Lowe, Pam K., Lindemeyer, Antje   +12 more
core   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source