ASD-Chat: An Innovative Dialogue Intervention System for Children with Autism based on LLM and VB-MAPP [PDF]
arXivEarly diagnosis and professional intervention can help children with autism spectrum disorder (ASD) return to normal life. However, the scarcity and imbalance of professional medical resources currently prevent many autistic children from receiving the necessary diagnosis and intervention.
arxiv
Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer
Molecular Oncology, EarlyView.We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi +26 more
wiley +1 more source
Psychoeducation: Issues and Directions for Research
Обозрение психиатрии и медицинской психологии имени В.М. Бехтерева, 2018 Psychoeducational interventions for schizophrenic patients and their families have shown impressive long-term effects on the course of illness. The authors conducted a review of scholarly journals and manuscripts indexed in commonly used search engines ...
N. D. Semenova +2 more
doaj
Learning Mixtures of Unknown Causal Interventions [PDF]
arXivThe ability to conduct interventions plays a pivotal role in learning causal relationships among variables, thus facilitating applications across diverse scientific disciplines such as genomics, economics, and machine learning. However, in many instances within these applications, the process of generating interventional data is subject to noise ...
arxiv
Molecular Oncology, EarlyView.Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé +7 more
wiley +1 more source
The Counseling Older Adults to Control Hypertension (COACH) trial: Design and methodology of a group-based lifestyle intervention for hypertensive minority older adults [PDF]
, 2013 Gbenga Ogedegbe +10 more
openalex +1 more source
Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM
Molecular Oncology, EarlyView.CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak +14 more
wiley +1 more source
A written self-help intervention for depressed adults comparing behavioural activation combined with physical activity promotion with a self-help intervention based upon behavioural activation alone: study protocol for a parallel group pilot randomised controlled trial (BAcPAc) [PDF]
, 2014 Paul Farrand +9 more
openalex +1 more source
Molecular Oncology, EarlyView.This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini +10 more
wiley +1 more source
Improving Engagement and Efficacy of mHealth Micro-Interventions for Stress Coping: an In-The-Wild Study [PDF]
arXivSustaining long-term user engagement with mobile health (mHealth) interventions while preserving their high efficacy remains an ongoing challenge in real-world well-being applications. To address this issue, we introduce a new algorithm, the Personalized, Context-Aware Recommender (PCAR), for intervention selection and evaluate its performance in a ...
arxiv