Results 141 to 150 of about 5,446,403 (344)
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard +12 more
wiley +1 more source
Psychoeducation: Issues and Directions for Research
Обозрение психиатрии и медицинской психологии имени В.М. Бехтерева, 2018 Psychoeducational interventions for schizophrenic patients and their families have shown impressive long-term effects on the course of illness. The authors conducted a review of scholarly journals and manuscripts indexed in commonly used search engines ...
N. D. Semenova +2 more
doaj
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
Internet-Based Self-Help Intervention for Procrastination: Randomized Control Group Trial Protocol [PDF]
, 2022 Zhou Ying, JIANHUA WANG
openalex +1 more source
Screening for lung cancer: A systematic review of overdiagnosis and its implications
Molecular Oncology, EarlyView.Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz +12 more
wiley +1 more source
Are the group-based interventions improving the functional exercise capacity and quality of life of frail subjects with chronic heart failure? [PDF]
J Frailty Sarcopenia Falls, 2020 Papathanasiou JV.
europepmc +1 more source
Who benefits from adolescent sleep interventions? Moderators of treatment efficacy in a randomized controlled trial of a cognitive‐behavioral and mindfulness‐based group sleep intervention for at‐risk adolescents [PDF]
, 2017 Matthew Blake +12 more
openalex +1 more source