Results 171 to 180 of about 6,543,351 (328)

Community-Driven Nursing Interventions: Enhancing Prevention and Early Detection of Chronic Kidney Disease in Hypertensive Patients at Non-communicable Disease Clinics

Journal of Pharmacy and Bioallied Sciences
Background: Chronic kidney disease (CKD) is one of the global key health issues; hypertension continues to be among the leading risk factors. This, therefore, calls for early detection and prevention with the aim of reducing the disease’s progression and
Sumathi Arumugam, Theranirajan Ethiraj, Shankar Shanmugam Rajendran, Palani Tamilselvi, Umamaheswari Periyasamy, Ghercy Elumalai, Saranya Subbaiya   +6 more
doaj   +1 more source

Using intervention mapping to develop a theory-driven, group-based complex intervention to support self-management of osteoarthritis and low back pain (SOLAS) [PDF]

, 2015
Deirdre A. Hurley, Laura Currie Murphy, David Hayes, Amanda Hall, Elaine Toomey, Suzanne McDonough, Chris Lonsdale, Nicola Walsh, Suzanne Guérin, James Matthews   +9 more
openalex   +1 more source

METTL3 knockout accelerates hepatocarcinogenesis via inhibiting endoplasmic reticulum stress response

FEBS Open Bio, EarlyView.
Liver‐specific knockout of N6‐methyladenosine (m6A) methyltransferase METTL3 significantly accelerated hepatic tumor initiation under various oncogenic challenges, contrary to the previously reported oncogenic role of METTL3 in liver cancer cell lines or xenograft models. Mechanistically, METTL3 deficiency reduced m6A deposition on Manf transcripts and
Bo Cui, Silin Tu, Haibo Li, Zhancheng Zeng, Ruiqi Xiao, Jing Guo, Xiaoqi Liang, Chang Liu, Lijie Pan, Wenjie Chen, Mian Ge, Xiaofen Zhong, Linsen Ye, Huaxin Chen, Qi Zhang, Yan Xu   +15 more
wiley   +1 more source

Evaluation of two study demands-resources-based interventions: a randomized controlled trial

Frontiers in Psychology
IntroductionHigher education students experience significant levels of exhaustion in their studies, yet there are limited evidence-based support programs available.
Lorena Sarah Körner, Timo Kortsch, Kerstin Rieder, Thomas Rigotti, Thomas Rigotti   +4 more
doaj   +1 more source

HypoAware-a brief and partly web-based psycho-educational group intervention for adults with type 1 and insulin-treated type 2 diabetes and problematic hypoglycaemia: design of a cost-effectiveness randomised controlled trial [PDF]

, 2015
Stefanie M.P.A. Rondags, Maartje de Wit, Maurits W. van Tulder, Michaëla Diamant, Frank J. Snoek   +4 more
openalex   +1 more source

Possible role of human ribonuclease dicer in the regulation of R loops

FEBS Open Bio, EarlyView.
R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik, Paulina Krzeminska, Anna Kurzynska‐Kokorniak   +2 more
wiley   +1 more source

Understanding the implementation and effectiveness of a group-based early parenting intervention: a process evaluation protocol [PDF]

, 2016
Gráinne Hickey, Sinéad McGilloway, Mairéad Furlong, Yvonne Leckey, Tracey Bywater, Michael Donnelly   +5 more
openalex   +1 more source

KCS1 and VIP1, the genes encoding yeast phosphoinositol pyrophosphate synthases, are required for Ca2+‐mediated response to dimethylsulfoxide (DMSO)

FEBS Open Bio, EarlyView.
Ca2+‐mediated response to DMSO was investigated in Saccharomyces cerevisiae cells expressing Ca2+‐dependent aequorin. Cell exposure to DMSO induced a cytosolic Ca2+ wave dependent on the integrity of the Cch1/Mid1 channel. Deletion of KCS1 or VIP1 genes encoding the phosphoinositol pyrophosphate (PP‐IP) synthases suppressed the DMSO‐induced Ca2 ...
Larisa Ioana Gogianu, Lavinia Liliana Ruta, Claudia Valentina Popa, Simona Ghenea, Ileana Cornelia Farcasanu   +4 more
wiley   +1 more source

The Effectiveness and Usability of Online, Group-Based Interventions for People With Severe Obesity: Protocol for a Systematic Review.

JMIR Res Protoc, 2021
Milne-Ives M, Swancutt D, Burns L, Pinkney J, Tarrant M, Calitri R, Chatterjee A, Meinert E.   +7 more
europepmc   +1 more source

Outcome of Home-Based Early Intervention for Autism in Sri Lanka: Follow-Up of a Cohort and Comparison with a Nonintervention Group [PDF]

, 2016
Hemamali Perera, Kamal Chandima Jeewandara, Sudarshi Seneviratne, Chandima Guruge   +3 more
openalex   +1 more source