Results 71 to 80 of about 1,195,505 (315)

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

Group-based social skills interventions for adolescents with higher-functioning autism spectrum disorder: a review and looking to the future

Adolescent Health, Medicine and Therapeutics, 2013
Camilla M McMahon,1 Matthew D Lerner,2,3 Noah Britton41Department of Curriculum and Instruction, Indiana University Bloomington, Bloomington, IN, USA; 2Department of Psychology, University of Virginia, Charlottesville, VA, USA; 3Department of Psychiatry ...
McMahon CM, Lerner MD, Britton N
doaj  

Using formative process evaluation to improve program implementation and accessibility of competitive group-based physical activity in the TEAM-PA trial

International Journal of Behavioral Nutrition and Physical Activity
Background This study demonstrates how formative process evaluation was used to assess implementation and improve dose and fidelity in the Together Everyone Achieves More Physical Activity (TEAM-PA) randomized controlled trial.
Allison M. Sweeney, Dawn K. Wilson, Nicole Zarrett, Timothy Simmons, Makayla Mansfield, Lindsay Decker   +5 more
doaj   +1 more source

miRNA‐29 regulates epidermal and mesenchymal functions in skin repair

FEBS Letters, EarlyView.
miRNA‐29 inhibits cell‐to‐cell and cell‐to‐matrix adhesion by silencing mRNA targets. Adhesion is controlled by complex interactions between many types of molecules coded by mRNAs. This is crucial for keeping together the layers of the skin and for regenerating the skin after wounding.
Lalitha Thiagarajan, Rosa Sanchez‐Alvarez, Chiho Kambara, Poojitha Rajasekar, Yuluang Wang, François Halloy, Jonathan Hall, Hans‐Jürgen Stark, Iris Martin, Petra Boukamp, Svitlana Kurinna   +10 more
wiley   +1 more source

Comparison of Instructor-Based and Parent-Based Interventions on Motor Development in Children with Developmental Coordination Disorder [PDF]

رشد و یادگیری حرکتی ورزشی, 2018
The purpose of this study was to compare instructor-based and parent-based interventions on motor development in 7 to 10 years old children with developmental coordination disorder.
Shima Abdolrahman Chapari, Mohammad Vaez Mousavi, Ali Kashi   +2 more
doaj   +1 more source

All in one stroke? Intervention Spaces for Dark Patterns [PDF]

arXiv, 2021
This position paper draws from the complexity of dark patterns to develop arguments for differentiated interventions. We propose a matrix of interventions with a \textit{measure axis} (from user-directed to environment-directed) and a \textit{scope axis} (from general to specific).
arxiv  

Spot‐14 and its paralog Spot‐14R regulate expression of metabolic and thermogenic pathway genes in murine brown and beige adipocytes

FEBS Letters, EarlyView.
Spot‐14 and Spot‐14R play distinct roles in regulating metabolism in brown and beige adipocytes. While both influence lipid and glucose pathways, Spot‐14 uniquely controls thermogenic gene expression. This dual regulation balances energy storage and heat production, highlighting potential therapeutic targets for obesity and metabolic disorders. Spot 14
Lidia Itzel Castro‐Rodríguez, Cristina Velez‐delValle, Claudia Patricia Hernández‐Mosqueira, Walid Kuri‐Harcuch   +3 more
wiley   +1 more source

Causal Abstraction with Soft Interventions [PDF]

arXiv, 2022
Causal abstraction provides a theory describing how several causal models can represent the same system at different levels of detail. Existing theoretical proposals limit the analysis of abstract models to "hard" interventions fixing causal variables to be constant values.
arxiv  

Interaction vesicles as emerging mediators of host‐pathogen molecular crosstalk and their implications for infection dynamics

FEBS Letters, EarlyView.
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke, Izadora Volpato Rossi, Marcel I. Ramirez   +2 more
wiley   +1 more source

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

Molecular Oncology, EarlyView.
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi, Jérome Vialaret, Christophe Hirtz, Catherine Alix‐Panabières   +3 more
wiley   +1 more source