Results 191 to 200 of about 41,735,200 (392)

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Developmental Profiling of Structural and Functional Maturation in Mouse Corpus Callosum. [PDF]

Glia
Johnson H, Beall M, Latifi S, Peng J, Sun W.   +4 more
europepmc   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

The Effect of Progressive Relaxation Exercises Applied to Individuals With Type 2 Diabetes on FATIQUE Level and Sleep Quality: A Randomised Controlled Study. [PDF]

Scand J Caring Sci
Vardar Inkaya B, Koç A, Genç B, Mumcu C, Güngör C, Ersoy R.   +5 more
europepmc   +1 more source

Rapid and Simple Determination of theEscherichia coli Phylogenetic Group

Applied and Environmental Microbiology, 2000
O. Clermont, S. Bonacorsi, É. Bingen
semanticscholar   +1 more source

Cryptanalysis of an Identity-Based Group-Oriented Signcryption Scheme in the Standard Model

, 2013
乐群 莫
openalex   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

The Impact of Real-Time Data Analytics on Infection Prevention and Control Practices in Ophthalmology: A Nursing Perspective on Patient Outcomes and Cost-Effectiveness. [PDF]

Nurs Health Sci
Chen Z, Wu S, Zhou Y, Tang C.
europepmc   +1 more source

A symmetric group action on the irreducible components of the Shi variety associated to $W(\widetilde{A}_n)$

, 2020
Nathan Chapelier‐Laget
openalex   +1 more source

Geographic differences in hemophilia-associated AIDS incidence in Pennsylvania. By the Pennsylvania AIDS Surveillance Study Group [PDF]

, 1987

openalex   +1 more source