Results 191 to 200 of about 2,101,930 (408)

In vitro Effects of Two Silver Electrodes on Select Wound Pathogens [PDF]

open access: yes, 1995
The use of electrical current to promote wound healing is well documented. However, little is understood about the effects of micro-amperage direct current (μADC) on growth of wound pathogens.
Kloth, Luther C.   +2 more
core   +1 more source

eIF4E Enriched Extracellular Vesicles Induce Immunosuppressive Macrophages through HMGCR‐Mediated Metabolic Rewiring

open access: yesAdvanced Science, EarlyView.
Here, it is revealed that ovarian cancer cells release extracellular vesicles enriched with eIF4E, which alters protein production in macrophages. This leads to increased expression of 3‐hydroxy‐3‐methyl‐glutaryl‐coenzyme A reductase (HMGCR), boosting cholesterol synthesis and activating an immunosuppressive pathway through X‐box binding protein 1 and ...
Sonam Mittal   +15 more
wiley   +1 more source

Dynamic Profiling of Lipoteichoic Acid (LTA) and/or Lipopolysaccharide (LPS) Positive Extracellular Vesicles in Plasma as Diagnostic and Prognostic Biomarkers for Bacterial Infection

open access: yesAdvanced Science, EarlyView.
Using nano‐flow cytometry, this study analyzes the dynamic characteristics of lipoteichoic acid (LTA) and/or lipopolysaccharide (LPS) positive extracellular vesicles in the bloodstream of patients with bacterial infections, providing promising biomarkers for rapid and accurate diagnosis.
Qianqian Gao   +10 more
wiley   +1 more source

Organoid Modeling of Mouse Anterior Tongue Epithelium Reveals Regional and Cellular Identities

open access: yesAdvanced Science, EarlyView.
The tongue's anterior epithelium is maintained by region‐specific stem/progenitor cells, yet in vitro models are limited. Long‐term expanding organoids are developed from adult mouse anterior tongue that retain region‐specific identity, cellular diversity, and gene regulatory features. These organoids differentiate into keratinocytes, Merkel‐like cells,
Seok‐Young Kim   +12 more
wiley   +1 more source

Peptide Electrostatic Modulation Directs Human Neural Cell Fate

open access: yesAdvanced Science, EarlyView.
This study explores the effect of charge on the bioactivity of peptide‐based supramolecular materials. The design of a peptide library with varying charges that self‐assemble into supramolecular fibers is presented, demonstrating how the surface charge of these fibers, used as artificial extracellular matrices, influences the fate of human neural ...
Laura Perez‐Chirinos   +10 more
wiley   +1 more source

AMINO GROUP FORMATION AND GLUTAMATE SYNTHESIS INSTREPTOCOCCUS BOVIS

open access: bronze, 1964
James J. Burchall   +2 more
openalex   +1 more source

Refractory Status Epilepticus and Therapeutic Uncertainties: a Comprehensive Review on Targeting Neuroinflammation and Rationale for Developing a Platform Trial

open access: yesAdvanced Science, EarlyView.
Refractory status epilepticus (RSE) is a life‐threatening neurological emergency with high rates of death and long‐term disability, but treatments for it are often based on limited evidence. RSE is now understood to involve neuroinflammation, which has led to the exploration of anti‐inflammatory and immunomodulatory agents like Tocilizumab. Traditional
Shanika Samarasekera   +12 more
wiley   +1 more source

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