Results 241 to 250 of about 121,872,801 (310)

Ordered assembly of Cas12a for better performance of CRISPR/Cas system with application to the diagnosis of dental caries

Interdisciplinary Medicine, EarlyView.
Here, we present a tetrahedral DNA framework (TDF)‐mediated Cas12a ordered assembly strategy. TDFs arrange CRISPR/Cas12a into ordered structures controllably, enhancing catalytic efficiency through localized Cas12a hotspots while maintaining spatial intervals to facilitate substrate diffusion.
Yining Zhao, Panpan Qiao, Yujing Zeng, Murtaza Sayed, Qin Mi, Juan Zhang, Genxi Li   +6 more
wiley   +1 more source

Molecular Characterization of the Group A Streptococcus Virulence-Regulatory System FasBCAX. [PDF]

Mol Microbiol
Baral S, Roshika R, Renshaw CP, Singh A, Prabhu A, Jain I, Woolsey R, Quilici D, Tal-Gan Y, Sumby P.   +9 more
europepmc   +1 more source

Enhanced CRISPR‐cas systems for genome editing and molecular diagnostics

Interdisciplinary Medicine, EarlyView.
This review systematically summarizes the major optimization strategies for CRISPR‐Cas systems, focusing on the engineering of Cas proteins, guide RNAs, reporter probes, and the incorporation of chemical additives. The aim is to enhance editing precision and diagnostic capability, thereby expanding the CRISPR system's potential for broader biomedical ...
Sheng Li, Han Li, Bojie Chen, Ling Jiang, Keyu Long, Jiaqi Lang, Xingxiang Pu, Erhu Xiong   +7 more
wiley   +1 more source

Comparison of Group A Streptococcus Antigen Detection and Pathogen Culture in Paediatric Infections. [PDF]

Infect Drug Resist
Yang M, Li Y, Chen L, Li X.
europepmc   +1 more source

Antibiotic Prophylaxis and Treatment of Neonatal Group B Streptococcus Disease in the Era of Antimicrobial Resistance. [PDF]

Antibiotics (Basel)
Tzialla C, Salomè S, Mondì V, Salvo V, Berardi A.   +4 more
europepmc   +1 more source

Whole-genome characterization of neonatal group B Streptococcus infection isolates and contemporaneous maternal colonizing isolates in Southwest China. [PDF]

Front Microbiol
Yan Z, Mu L, Miao C, Fu Y, Liu L, Liu X, Luo J, Wu W, Ling J, Liang L, Cui Y, Jiang Y, Kuang L.   +12 more
europepmc   +1 more source

Streptococcus milleri group

Japanese Journal of Pediatric Pulmonology, 1994
openaire   +2 more sources

T cells in Group A <i>Streptococcus</i> infection: protection or pathology? [PDF]

Front Cell Infect Microbiol
Mathew L, Ali M, Townsley H, Halliday A, Klenerman P, de Silva TI, Goenka A.   +6 more
europepmc   +1 more source

New Strategies for Preventing Perinatal Group B Streptococcus (GBS) Infections. [PDF]

Pathogens
Kaminska D, Ratajczak M, Nowicka W, Dlugaszewska J, Gajecka M.   +4 more
europepmc   +1 more source