Results 251 to 260 of about 1,880,201 (344)

Serotype Distribution, Virulence, and Antibiotic Resistance Genomic Characterization of Group B Streptococcus - China, 1998-2024. [PDF]

China CDC Wkly
Ren X, Liu X, Che Y, Yang L, Mao Y, Li M, Sun Z, Bai X, Gao H, Wang Y, Wang D.   +10 more
europepmc   +1 more source

Targeting Ubiquitin‐Specific Protease 7 with Novel 5‐Amino‐Pyrazole Inhibitors: Design, Synthesis, and Biological Evaluation

ChemMedChem, EarlyView.
Ubiquitin‐specific protease 7 (USP‐7) is a novel target for anticancer therapy. To further extend the structure–activity relationships of the previously USP‐7 inhibitor STIRUR‐41, a library of 5‐aminopyrazoles is reported. 1d shows a potency comparable to lead compound STIRUR‐41 and promising in silico and in vitro pharmacokinetic properties ...
Matteo Lusardi, Elva Morretta, Andrea Spallarossa, Maria Chiara Monti, Camillo Rosano, Erika Iervasi, Marco Ponassi, Matteo Mori, Fiorella Meneghetti, Chiara Brullo   +9 more
wiley   +1 more source

Targeted Delivery of Lidocaine in Breast Cancer Cells via Zeolitic Imidazolate Framework‐8 Nanoparticles

ChemPhysChem, EarlyView.
Drug repositioning of lidocaine from local anesthetic to theranostic agent for breast cancer cells is enhanced by its encapsulation inside ZIF‐8 metal–organic framework. The aim of this article is to use zeolitic imidazolate framework‐8 (ZIF‐8) metal–organic frameworks (MOFs) as drug delivery system for lidocaine, a local anesthetic with recently ...
Nicola di Nicola, Luca Giacchi, Marco Vandone, Marcello Crucianelli, Leonardo Guidoni, Valentina Colombo, Nadia Rucci, Andrea Lazzarini   +7 more
wiley   +1 more source

A case of penicillin-resistant group B Streptococcus isolated from a patient in the UK. [PDF]

J Antimicrob Chemother
McGuire E, Ready D, Ellaby N, Potterill I, Pike R, Hopkins KL, Guy RL, Lamagni T, Mack D, Scobie A, Warren S, Brown CS, Coelho J.   +12 more
europepmc   +1 more source

Hierarchical clustering of clinical and flow cytometry parameters is associated with deterioration in patients with community‐acquired pneumonia in the emergency department: A preliminary study

Cytometry Part B: Clinical Cytometry, EarlyView.
ABSTRACT Anticipating the evolution of septic patients with community‐acquired pneumonia (CAP) is challenging for front‐line physicians in the Emergency Department (ED). Prognosis depends mainly on early identification, antibiotics, organ support, but also immune status.
Thomas Lafon, Robin Jeannet, Thomas Daix, Guillaume Monneret, Jean Feuillard   +4 more
wiley   +1 more source

High-level aminoglycoside resistance in group A, B, G, D (Streptococcus bovis), and viridans streptococci

, 1982
T Horodniceanu, Annie Buu-Hoï, F Delbos, G Bieth   +3 more
openalex   +1 more source

Lipid Nanoparticles as an Effective Strategy for Protecting Bioactive Compounds in Passion Fruit Seed Oil

European Journal of Lipid Science and Technology, EarlyView.
This schematic illustrates the encapsulation of Passiflora edulis seed oil (PFSO) into lipid nanoparticles (LNP‐PFSO), transforming waste into value. The nanoparticles, optimized for size (126 nm, PDI: 0.19), were characterized (SEM, FTIR, XRD) and tested for antimicrobial and antioxidant activities, with applications in food fortification or active ...
Letícia A. D. Morais, Mateus C. Viana, Natalha V. Pinto, Ana P. Rodrigues, Kelly C. Kato, Vívian M. Benassi, Franciele M. P. Molina, Guilherme Carneiro   +7 more
wiley   +1 more source

Detection of Hypervirulent ST-17 Clone Among Clinical Group B Streptococcus Isolates Using MALDI-TOF MS and PCR. [PDF]

Infect Dis Clin Microbiol
Malkoçoğlu G, Bulut ME, Bayraktar B, Otlu B, Aktaş E.   +4 more
europepmc   +1 more source

Studies on Group B β-Hemolytic Streptococcus. I. Isolation and Partial Characterization of an Extracellular Toxin

, 1981
Carl G. Hellerqvist, Jorge Rojas, Robert S. Green, Sara Sell, Håkan Sundell, Mildred T. Stahlman   +5 more
openalex   +1 more source

Hydrogen peroxide ‐ responsive aminoferrocene prodrugs

European Journal of Organic Chemistry, Accepted Article.
Aminoferrocene (AF)‐based prodrugs are activated in cancer cells through reactions with H₂O₂ and other reactive oxygen species (ROS), generating electron‐rich AF’s. These, in turn, induce the production of highly toxic O2·‐ and HO·, leading to cancer cell death.
Marlies Körber, Jennifer Rühle, Fabian Halter, Andriy Mokhir   +3 more
wiley   +1 more source