Results 81 to 90 of about 384,194 (283)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Group acceptance sampling plans for lifetimes following an odds exponential log logistic distribution

open access: yesSri Lankan Journal of Applied Statistics, 2016
A group acceptance sampling plan is developed for odds exponential log logistic distribution (OELLD) based on truncated lifetime with a known shape parameter. At a specified level of consumer risk and at the predefined test termination time, we derived the minimum number of groups required for a given group size and the acceptance number using the two ...
Rosaiah Kanaparthi   +3 more
openaire   +2 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Lunar TV - Reliability Evaluation Plan [PDF]

open access: yes, 1966
Reliability plan for lunar TV camera ...
Kraeger, G. W.
core   +1 more source

Fuzzification of quantitative data to predict tumour size of colorectal cancer [PDF]

open access: yes, 2017
Regression analysis has become more popular among researchers as a standard tool in analyzing data. This paper used fuzzy linear regression model (FLRM) to predict tumour size of colorectal cancer (CRC) data in Malaysia.
Amir Hamzah, Nor Shamsidah   +5 more
core   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Profiling and understanding student information behaviour: Methodologies and meaning [PDF]

open access: yes, 2003
This paper draws on work conducted under the Joint Information Systems Committee (JISC) User Behaviour Monitoring and Evaluation Framework to identify a range of issues associated with research design that can form a platform for enquiry about knowledge ...
Rowley, Jennifer
core   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Burr III Scaled Inverse Odds Ratio‐Weibull Distribution for Modeling Asymmetric Medical and Engineering Data

open access: yesEngineering Reports
This article introduces the novel five‐parameter Burr III Scaled Inverse Odds Ratio‐Weibull (B‐SIOR‐W) distribution, a flexible extension of the classical two‐parameter Weibull model, specifically engineered to model asymmetric data prevalent in medical ...
Sadia Nadir   +6 more
doaj   +1 more source

Home - About - Disclaimer - Privacy