Results 111 to 120 of about 13,701,338 (294)
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Graphs of group actions and group actions on trees
Bass-Serre theory provides a powerful framework for studying group actions on trees. While extremely effective for structural questions in group theory, it is less suited to the systematic construction of group actions with prescribed local behaviour. Motivated by local-to-global constructions such as the Burger-Mozes universal groups and local action ...
Lehner, Florian +3 more
openaire +2 more sources
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
In the foreground, a woman smiling at an alpaca. In the background, a group of people.
Freak freeze conditions in Peru Practical Action is working with remote indigenous Andean communities to help protect their alpacas and potato varieties to improve livelihoods and biodiversity thereby reducing vulnerability to climate change.
Practical Action Peru
core
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Scene variability affects action decisions, confidence and behaviour dynamics
Humans often unfold their actions within complex, variable environments. While such variability is sometimes irrelevant to task success, it could still influence both action decisions and confidence in their outcome.
David Aguilar-Lleyda +3 more
doaj +1 more source
A large group of natives posing for a photo, with the hills in the background.
Freak freeze conditions in Peru Practical Action is working with remote indigenous Andean communities to help protect their alpacas and potato varieties to improve livelihoods and biodiversity thereby reducing vulnerability to climate change.
Practical Action Peru
core
The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source

