Results 131 to 140 of about 13,701,338 (294)
Gyrogroup actions: A generalization of group actions
This article explores the novel notion of gyrogroup actions, which is a natural generalization of the usual notion of group actions. As a first step toward the study of gyrogroup actions from the algebraic viewpoint, we prove three well-known theorems in group theory for gyrogroups: the orbit-stabilizer theorem, the orbit decomposition theorem, and the
openaire +3 more sources
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Project at Bocatoma The Eastern slopes of the Andes in North Peru are among the least developed parts of the country with the majority of people living in remote villages with little or no access to grid electricity.
Practical Action Peru
core
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
The Eastern slopes of the Andes in North Peru are among the least developed parts of the country with the majority of people living in remote villages with little or no access to grid electricity.
Practical Action Peru
core
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
This article tells a 'learning conference' story about the establishment of a local action learning and action research (ALAR) Conversation Group in a regional city in Australia, which occurred between the Action Learning and Action Research Association (
Lynn, Robyn, Redman-MacLaren, Michelle
core
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
The Eastern slopes of the Andes in North Peru are among the least developed parts of the country with the majority of people living in remote villages with little or no access to grid electricity.
Practical Action Peru
core
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source

