Results 141 to 150 of about 13,701,338 (294)

So you think you are doing action research? Indicators of enactment of participatory action research in higher education

open access: yes, 2013
Action Research is being adopted as a research and project method for the higher education learning and teaching sector. A researcher new to Action Research may need to be scaffolded through the process of validating their research as Action Research ...
Harvey, Marina
core  

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

A group of children

open access: yes, 2015
Our aim is to develop the capacities of the communities settled in the Alto Mayo area to face and reduce the crisis that affects their livelihoods. The destruction of the forest, together with conflicts between the Colono (impoverished landless peasants ...
Practical Action Peru
core  

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

A group of kamayoq

open access: yes, 2015
In the Andean province of Canchis, the main activity is raising alpacas, llamas and sheep and growing native potatoes. On average, each family owns 50 alpacas or llamas, obtaining an income of about $300 a year.
Practical Action Peru
core  

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

GROUP ACTION INDUCED AVERAGING FOR HARDI PROCESSING. [PDF]

open access: yesProc IEEE Int Symp Biomed Imaging, 2012
Cetingül HE   +4 more
europepmc   +1 more source

Group action-stabilizer graph of group actions of a group on a set

open access: yes
In this paper we introduce the group action-stabilizer graph $GAS(G)$ of a group $G$ on a set $X$ with vertex set as the collection of all the group actions of $G$ on $X$, and any two vertices $ϕ$ and $ψ$ are adjacent if and only if the non-trivial subgroups $\cap G_x^ϕ$ and $\cap G_x^ψ$ of $G$ intersect non-trivially, where $G_x^ϕ$ and $G_x^ψ$ are two
Hazarika, Nepur Ranjan   +1 more
openaire   +2 more sources

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

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