Results 131 to 140 of about 710,895 (306)

Agency working in Britain: character, consequences and regulation [PDF]

Debate over the nature of temporary agency work has intensified in recent times, spurred on by a proposed European directive and by speculation about links with the much heralded ‘knowledge’ economy.
Chris Forde, Gary Slater
core  

Christian List and Philip Pettit's Group agency: the possibility, design, and status of corporate agents. Oxford: Oxford University Press, 2011, 240 pp.

Erasmus Journal for Philosophy and Economics, 2011
Carlo Martini
doaj   +1 more source

Striving for group agency: threat to personal control increases the attractiveness of agentic groups. [PDF]

Front Psychol, 2015
Stollberg J, Fritsche I, Bäcker A.
europepmc   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Questioning Two Common Assumptions concerning Group Agency and Group Cognition [PDF]

In this paper, we identify two common assumptions underlying popular accounts of group agency. The first assumption is that paradigmatic cases of agency are to be identified with individual organisms, typically human beings. The second assumption is that
Peck, Zachary, Chemero, Anthony
core  

Investigation on environmental factors contributing to bispecific antibody stability and the reversal of self-associated aggregates

Bioresources and Bioprocessing
Bispecific antibodies (bsAbs) hold promises for enhanced therapeutic potential surpassing that of their parental monoclonal antibodies. However, bsAbs pose great challenges in their manufacturing, and one of the common reasons is their susceptibility to ...
Nattha Ingavat, Nuruljannah Dzulkiflie, Jia Min Liew, Xinhui Wang, Eunice Leong, Han Ping Loh, Say Kong Ng, Yuansheng Yang, Wei Zhang   +8 more
doaj   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Multi-agency working

, 2008
This chapter, therefore, examines the case for a strategic approach to joined-up services by reviewing the development and operation of multi-agency working in Scottish education, and considers the professional imperatives for collaboration between ...
Connelly, Graham
core  

Estimating COVID-19 incidence and prevalence using lateral flow tests in England and Scotland, 2023-2024

Nature Communications
SARS-CoV-2 continues to cause substantial morbidity and mortality, particularly in winter. During the SARS-CoV-2 pandemic, community prevalence surveys provided detailed monitoring of infection levels.
Martyn Fyles, Jonathon Mellor, Robert S. Paton, Christopher E. Overton, Alexander M. Phillips, Alex Glaser, Thomas Ward   +6 more
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source