Results 111 to 120 of about 710,895 (306)

Assessing the generation and dispersal of respiratory particles using upper respiratory commensal bacteria as index organisms for respiratory pathogens

Scientific Reports
There is a need to better understand the dispersal and spread of respiratory pathogens. However, carrying out controlled microbiology-based simulation studies is difficult, particularly if the target organism is highly pathogenic or is currently unknown.
Patricia Barkoci, Wilhemina D’Costa, Neville Q. Verlander, Nicola Yaxley, Ginny Moore   +4 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Salmon Research Agency of Ireland, Annual Report No. 37, 1992

, 1993
This report is a predecessor to our current Newport Research Facility, Annual Reports. Prior to the Marine Institute, this work was carried out by the Salmon Research Trust of Ireland, and later the Salmon Research Agency of Ireland.
Marine Institute, Salmon Research Agency of Ireland   +1 more
core  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Salmon Research Agency of Ireland, Annual Report No. 38, 1993

, 1994
This report is a predecessor to our current Newport Research Facility, Annual Reports. Prior to the Marine Institute, this work was carried out by the Salmon Research Trust of Ireland, and later the Salmon Research Agency of Ireland.
Marine Institute, Salmon Research Agency of Ireland   +1 more
core  

“I definitely cannot afford to be feeling poorly if there’s no need to be”: a qualitative evaluation of antiviral uptake following suspected occupational exposure to avian influenza

BMC Public Health
Background Growing numbers of people have been potentially exposed to avian influenza (AI), as the United Kingdom has managed the largest and most sustained series outbreaks in recent years. Antiviral medication is recommended for exposed individuals for
Riinu Pae, Lucy Findlater, Richard Amlôt, Fernando Capelastegui, Gavin Dabrera, Clare Humphreys, Jharna Kumbang, Isabel Oliver   +7 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Salmon Research Agency of Ireland, Annual Report No. 43, 1998

, 1999
This report is a predecessor to our current Newport Research Facility, Annual Reports. Prior to the Marine Institute, this work was carried our by the Salmon Research Trust of Ireland, and later the Salmon Research Agency of Ireland.
Marine Institute, Salmon Research Agency of Ireland   +1 more
core  

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Disjointed Service: An English Case Study of Multi-Agency Provision in Tackling Child Trafficking

, 2015
This paper examines the issue of child trafficking in the United Kingdom and of multi-agency responses in tackling it. The UK, as a signatory to the recent trafficking protocols, is required to implement measures to identify and support potential ...
Zeibeda Sattar, Sattar, Zeb, Rob A. Hornsby, Harvey, Jackie, Jackie H. Harvey, Hornsby, Robert   +5 more
core   +1 more source