Results 151 to 160 of about 20,605,933 (257)

Expression, Purification, and Microscopy‐Based Assays for Engineered Recombinant Tyrosinated, Detyrosinated, and Δ2 Human Tubulin

Cytoskeleton, EarlyView.
ABSTRACT Microtubules are noncovalent polymers assembled from α/β tubulin dimers. Their structure, dynamics and interaction with effectors are regulated through the expression of diverse tubulin isotypes and chemically diverse posttranslational modifications, also known as the “tubulin code.” Understanding the biophysical correlates between tubulin ...
Jiayi Chen, Agnieska Szyk, Antonina Roll‐Mecak   +2 more
wiley   +1 more source

Group B Streptococcus awareness month: vaccine and challenges underway

International Journal of Infectious Diseases, 2021
Tatiana Castro Abreu Pinto, Laura Maria Andrade Oliveira, Natália Silva da Costa, Amanda de Assis Rocha, André Rio Tinto de Matos Freire, Carollina Moreira Franquelino Gutierrez, Crislaine Mateus Santos, Danielle Cristina dos Santos Silva Alvim, Débora da Costa Morato Nery, Isabella Bittencourt Ferreira Pinto, Leandro Corrêa Simões, Lucas Cecílio Vilar, Luísa de Miranda Basto Silva, Luiz Marcelo Rocha da Silva, Júnior, Maria Luiza Rios Santos, Natália Alves de Araújo, Tatiane Nobre Pinto, Victoria Caroline Neves Leite   +17 more
doaj   +1 more source

Gestational age modifies associations between Group B Streptococcus genomic characteristics and postnatal age at disease onset. [PDF]

Nat Commun
Murra M, Henriksen TB, Andersen M, Pedersen K, Engberg JH, Ellermann-Eriksen S, Nielsen HL, Hertz FB, Lauritsen NN, Khalil M, Møller JK, Slotved HC, Nielsen SY.   +12 more
europepmc   +1 more source

Active Bacterial Core Surveillance (ABCs) Report: Emerging Infections Program Network: Group B Streptococcus, 2014 [PDF]

ABCs Areas: California (3 county San Francisco Bay area); Colorado (5 county Denver area); Connecticut (children < 1 year); Georgia (20 county); Maryland; Minnesota; New Mexico; New York (15 county Rochester and Albany areas); Oregon (3 county Portland ...

core  

Opsoclonus in Pediatric Patients: Differential Diagnosis and a Practical Approach to Evaluation

Annals of the Child Neurology Society, EarlyView.
ABSTRACT Opsoclonus is an ocular dyskinesia characterized by involuntary, arrhythmic, multidirectional saccades. In pediatrics, opsoclonus is most commonly attributed to the rare neuroinflammatory disorder opsoclonus‐myoclonus‐ataxia syndrome (OMAS), typically considered a paraneoplastic syndrome associated with neural crest tumors. However, opsoclonus
Aubrey C. Reed, Supreet S. Randhawa, Jason H. Peragallo, Prabhumallikarjun Patil, Grace Gombolay, Varun Kannan   +5 more
wiley   +1 more source

Neonatal Group B Streptococcus sepsis with negative maternal screening: a case report. [PDF]

BMC Pediatr
Liu Y, Chang L, Chen GC, Wang Y.
europepmc   +1 more source

Long‐Acting Therapeutics in Pediatric Health: Bridging Innovation and Access

Clinical Pharmacology &Therapeutics, EarlyView.
Children have distinct therapeutic needs arising from age‐dependent physiology, disease epidemiology, formulation requirements, dosing considerations, and safety vulnerabilities. Despite substantial reductions in childhood mortality over the past three decades, nearly 5 million children under five died in 2023, with infectious diseases continuing to ...
Prajith Venkatasubramanian, Moherndran Archary, Daniel B. Hawcutt, Rachel Daley, Edmund Capparelli, Adeniyi Olagunju   +5 more
wiley   +1 more source

Innovative epitope-based ELISA assay for detecting Group B Streptococcus carriage in pregnant women. [PDF]

Appl Microbiol Biotechnol
Brzychczy-Włoch M, Dobrut A, Drożdż K, Malska-Woźniak A, Pabian W, Górska S, Brzozowska E, Gamian A.   +7 more
europepmc   +1 more source

Investigation of the molecular basis of virulence of Streptococcus equi [PDF]

Equine strangles is a purulent lymphadenitis of the head and neck and is caused by Streptococcus equi ssp equi remaining a worldwide, endemic infection that represents around 30% of all annually recorded incidents of equine disease.
Barrett, Lee
core  

Epilepsy‐associated SCN2A‐L1342P mutation drives network hyperexcitability and widespread transcriptomic changes in human cortical organoids

Epilepsia, EarlyView.
Abstract Objective SCN2A pathogenic mutations, such as the recurrent heterozygous Nav1.2‐L1342P, are monogenic causes of epilepsy. In this human‐induced pluripotent stem cell–derived model system, we aim to investigate the molecular and cellular mechanisms underlying SCN2A‐L1342P‐associated pathology. Methods Using a human male induced pluripotent stem
Maria I. Olivero‐Acosta, Morgan Robinson, Zhefu Que, Zaiyang Zhang, Karen V. Salazar‐Salazar, Hope Elizabeth Harlow, Vinayak Shankar, Seoyeon Hong, Muhan Wang, Conrad M. Otterbacher, Hina Kadono, Manasi Halurkar, Harish Kothandaraman, Nadia Atallah Lanman, Trang Nguyen, Kyle Wettschurack, Benjamin Zirkle, Layan Yunis, Ningren Cui, Xiaoling Chen, Jingliang Zhang, Jiaxiang Wu, William C. Skarnes, Chongli Yuan, Feng Guo, Megan Abbott, Yang Yang   +26 more
wiley   +1 more source