Results 51 to 60 of about 20,605,933 (257)

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

FEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

Genetic diversity of Streptococcus suis isolates as determined by comparative genome hybridization [PDF]

, 2011
Background Streptococcus suis is a zoonotic pathogen that causes infections in young piglets. S. suis is a heterogeneous species. Thirty-three different capsular serotypes have been described, that differ in virulence between as well as within serotypes.
Smith, H.E., Schultsz, C, Baums Christoph G, de Bree, F.M., de Greeff Astrid, Ngo Thi, Hoa, Thi, Hoa Ngo, Christoph G Baums, Thi, HN, Hoa, N.T., Thi Hoa, Bree, F.M., de, Constance Schultsz, Stockhofe-Zurwieden, Norbert, Greeff, A., de, Wisselink Henk J, de Bree, Freddy M., Henk J Wisselink, Hoa Thi, Schultsz, Constance, Smith Hilde E, Hilde E Smith, Baums, Christoph G., Wisselink, H.J., de Bree, FM, Freddy M de Bree, Stockhofe-Zurwieden, N, Stockhofe-Zurwieden, N., Schultsz Constance, Schultsz, C., de Greeff, A, Smith, HE, Baums, CG, de Greeff, Astrid, de Bree Freddy M, de Greeff, A., Baums, C.G., Smith, Hilde E., Stockhofe-Zurwieden Norbert, Wisselink, HJ, Norbert Stockhofe-Zurwieden, Wisselink, Henk J., Astrid de Greeff   +42 more
core   +2 more sources

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Correlates of vaginal colonization with group B streptococci among pregnant women

Journal of Global Infectious Diseases, 2010
Background: A study of genital colonization by group B streptococcus (GBS) was conducted in pregnant women in their third trimester, which is a known risk factor of morbidity and mortality among newborns.
Tsering Chomu Dechen, Kar Sumit, Pal Ranabir   +2 more
doaj   +1 more source

A Mouse Nasopharyngeal Colonization Model for Group A Streptococcus

, 2020
Group A Streptococcus (GAS) often exists as an asymptomatic colonizer of the upper respiratory tract in humans. Unsurprisingly, a high proportion of symptomatic infections caused by GAS include pharyngitis.
Jacelyn M. S. Loh, Adrina H. J. Khemlani, Loh, JMS, Thomas Proft, Khemlani, AHJ, Proft, Thomas   +5 more
core   +1 more source

Metabolic and Fluid Biomarkers Support Microglia Activation in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Amyotrophic lateral sclerosis is an incurable neurodegenerative disease involving motor neuron degeneration and metabolic and immune dysfunction. We combined clinical data, cerebrospinal fluid biomarkers and fluorodeoxyglucose positron emission tomography with magnetic resonance imaging to investigate the role of reactive microglia in disease ...
Matteo Zanovello, Francesca Serani, Alen Bebeti, Federica Paredi, Giulia Quadrio, Andrea Fortuna, Giacomo Maria Minicuci, Elena Pegoraro, Annachiara Cagnin, Diego Cecchin, Gianni Sorarù   +10 more
wiley   +1 more source

Akkermansia muciniphila impacts group B Streptococcus vaginal colonization

mBio
Streptococcus agalactiae, or group B Streptococcus (GBS), is an opportunistic pathogen that asymptomatically colonizes the vaginal tract of up to 30% of healthy individuals. However, during pregnancy, it is associated with adverse pregnancy outcomes, and
Stephanie M. Marroquin, Shirli Cohen, Melody N. Neely, Kelly S. Doran   +3 more
doaj   +1 more source

Genome specialization and decay of the strangles pathogen, Streptococcus equi, is driven by persistent infection [PDF]

, 2015
The authors would like to thank the Horserace Betting Levy Board for funding the analysis of the eqbE mutant (ref: Vet/prj/758). The Horse Trust funded the collection of isolates from UK outbreaks of strangles (G1606).
Paillot, Romain, Waller, Andrew S, Steward, Karen F, Robinson, Carl, Holden, Matthew T G, Harris, Simon R, Parkhill, Julian, Webb, Katy S   +7 more
core   +1 more source

Patient‐Derived 3D Heart‐On‐a‐Chip Model of Dilated Cardiomyopathy With Embedded Bead‐Based Mapping of Tissue Contractility

Advanced Healthcare Materials, EarlyView.
A heart‐on‐a‐chip model of dilated cardiomyopathy is developed from patient‐derived induced pluripotent stem cells. The model recapitulates key disease phenotypes and enables functional assessment through integrated bead‐based tracking and pillar deflection measurements.
Ali Mousavi, Ludovic Mouttet, Shihao Cui, Yasaman Hekmatnia, Mehran Mottahedi, Ida Derish, Naimeh Rafatian, Mark Aurousseau, Gregor Andelfinger, Renzo Cecere, Houman Savoji   +10 more
wiley   +1 more source

The identification of Streptococcus pneumoniae [PDF]

, 2006
ei tietoa saavutettavuudesta unknown ...
Kaijalainen, Tarja
core