Results 41 to 50 of about 359,367 (303)

Efectividad de la autotoma del exudado vaginorrectal para el cribado prenatal de la infección por Streptococcus agalactiae. Estudio GALL

Atención Primaria, 2022
Resumen: Objetivo: Evaluar la efectividad de la autotoma del exudado vaginorrectal para el cribado prenatal de la infección por EGB e identificar barreras y facilitadores que encuentra la gestante para esta intervención.
Laura Nebreda-Martín, Aintzane Albisu-del Campo, Leire Valle-Ruiz de Larrea, Gema González-Rodríguez, Eunate Arana-Arri, Carmen Paz-Pascual   +5 more
doaj   +1 more source

Human streptococcus agalactiae strains in aquatic mammals and fish [PDF]

, 2013
<p>Background: In humans, Streptococcus agalactiae or group B streptococcus (GBS) is a frequent coloniser of the rectovaginal tract, a major cause of neonatal infectious disease and an emerging cause of disease in non-pregnant adults.
Crumlish, M., Dagleish, M.P., Delannoy, C.M.J., Fontaine, M.C., Foster, G., Pollock, J., Turnbull, J.F., Zadoks, R.N.   +7 more
core   +5 more sources

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Understanding Factors in Group B Streptococcus Late-Onset Disease

Infection and Drug Resistance, 2021
Alberto Berardi,1 Viola Trevisani,2 Antonella Di Caprio,2 Jenny Bua,3 Mariachiara China,4 Barbara Perrone,5 Rossella Pagano,6 Laura Lucaccioni,7 Silvia Fanaro,8 Lorenzo Iughetti,2,7 Licia Lugli,1 Roberta Creti9 1Terapia Intensiva Neonatale, Azienda ...
Berardi A, Trevisani V, Di Caprio A, Bua J, China M, Perrone B, Pagano R, Lucaccioni L, Fanaro S, Iughetti L, Lugli L, Creti R   +11 more
doaj  

Correlates of vaginal colonization with group B streptococci among pregnant women

Journal of Global Infectious Diseases, 2010
Background: A study of genital colonization by group B streptococcus (GBS) was conducted in pregnant women in their third trimester, which is a known risk factor of morbidity and mortality among newborns.
Tsering Chomu Dechen, Kar Sumit, Pal Ranabir   +2 more
doaj   +1 more source

Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion

FEBS Open Bio, EarlyView.
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng, Souvik Datta, Derrick R. Samuelson   +2 more
wiley   +1 more source

Group B Streptococcus (Streptococcus agalactiae) Screening During Pregnancy

Journal of Rawalpindi Medical College, 2014
Background:An audit trial was conducted to review our practice of Universal GBS screening for our pregnant patients and its effect on fetal outcome.
Jahan Ara Saeed
doaj  

Capsular Typing Method for Streptococcus agalactiae Using Whole-Genome Sequence Data. [PDF]

, 2016
Group B streptococcus (GBS) capsular serotypes are major determinants of virulence and affect potential vaccine coverage. Here we report a whole-genome-sequencing-based method for GBS serotype assignment. This method shows strong agreement (kappa of 0.92)
Berkley, James A, Crook, Derrick W, Efstratiou, Androulla, Jones, Nicola, Modernising Medical Microbiology Informatics Group, Patel, Darshana, Seale, Anna C, Sheppard, Anna E, Turner, Claudia, Turner, Paul, Vaughan, Alison, Walker, A Sarah   +11 more
core   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source