Results 71 to 80 of about 359,357 (309)

Lipid Nanoparticles for the Delivery of CRISPR/Cas9 Machinery to Enable Site‐Specific Integration of CFTR and Mutation‐Agnostic Disease Rescue

Advanced Functional Materials, EarlyView.
Lipid nanoparticles (LNPs) are optimized to co‐deliver Cas9‐encoding messenger RNA (mRNA), a single guide RNA (sgRNA) targeting the endogenous cystic fibrosis transmembrane conductance regulator (CFTR) gene, and homologous linear double‐stranded donor DNA (ldsDNA) templates encoding CFTR.
Ruth A. Foley, Paul G. Ayoub, Vrishti Sinha, Colin Juett, Alicia Sanoyca, Emily C. Duggan, Lindsay E. Lathrop, Priyanka Bhatt, Kevin Coote, Beate Illek, Brigitte N. Gomperts, Donald B. Kohn, Steven J. Jonas   +12 more
wiley   +1 more source

Progress in the prevention of group B Streptococcus

Vaccine: X
Group B Streptococcus (GBS) is a significant bacterial pathogen that poses substantial health risks, particularly among neonates and pregnant women. It is responsible for a range of severe infections, including sepsis, pneumonia, and meningitis, which ...
Shuang Gao, Xiaona Wang, Xiaojuan Sun, Kangyi Li   +3 more
doaj   +1 more source

Group B Streptococcus meningitis. [PDF]

, 2013
Abstract This chapter reviews the current understanding of the physiopathology of group B streptococcal (GBS) meningitis, highlighting important bacterial virulence factors and host interactions that promote disease progression. The relationship between bacteraemia and the development of GBS meningitis, and the mechanisms of GBS immune evasion,
V. Nizet, K. S. Doran
openaire   +1 more source

Group B streptococcus infection

, 2021
Group B streptococcus (GBS) (Streptococcus agalactiae), a Gram-positive coccus, is one of the major causes of maternal or neonatal severe infection and sepsis. Maternal infection associated with GBS includes acute chorioamnionitis, endometritis, and urinary tract infection.
Jessica Winn, Hung N. Winn
openaire   +2 more sources

Interconnected Porous Hydrogels with Tunable Anisotropy Through Aqueous Emulsion Bioprinting

Advanced Functional Materials, EarlyView.
A 3D bioprintable microporous bioink is developed using an aqueous two‐phase system (ATPS) composed of extracellular matrix (ECM) mimetic biopolymers. The ATPS bioink enables the fabrication of interconnected porous architectures with up to 70% porosity, supporting long‐term cell viability and 3D cell alignment, enabling a simultaneous generation of ...
Hugo Edgar‐Vilar, Francisca P. Correia, Inês M. Freitas, Vítor M. Gaspar, João F. Mano   +4 more
wiley   +1 more source

Phenotypical characteristics of group B streptococcus in parturients

Brazilian Journal of Infectious Diseases
Colonization by Group B Streptococcus (GBS) is highly prevalent among pregnant women, with prevalence rates ranging between 4% and 30%. The infection may be transmitted vertically and may result in serious neonatal consequences.
Jose Antonio Simoes, Valeria Moraes Neder Alves, Sergio Eduardo Longo Fracalanzza, Rodrigo Pauperio Soares de Camargo, Lenir Mathias, Helaine Maria Besteti Pires Milanez, Eliane Melo Brolazo   +6 more
doaj   +1 more source

Impact of Surface Functionalization on NV Quantum Properties: Implications for Biosensing with Fluorescent Nanodiamonds

Advanced Functional Materials, EarlyView.
Fluorescent nanodiamonds (fNDs) have emerged as an invaluable quantum sensing platform for biological and biochemical systems. This paper investigates the influence of common surface functionalization strategies for bioconjugation on the quantum properties of nitrogen vacancy (NV) centers in nanodiamonds.
Anja Sadžak, Iván Pérez, Mateja Guimarães, Lukas Spantzel, Fedor Jelezko, Michael Börsch, Anke Krueger   +6 more
wiley   +1 more source

A survey of the incidence of neonatal sepsis by group B Streptococcus during a decade in a Brazilian maternity hospital

Brazilian Journal of Infectious Diseases
Group B Streptococcus (GBS) is the main etiological agent of neonatal sepsis in developed countries, however there is no detailed information on its incidence in Brazil.
Edinéia Vaciloto, Rosana Richtmann, Helenilce de Paula Fiod Costa, Elisa Junko Ura Kusano, Maria Fernanda Branco de Almeida, Eduardo Rahme Amaro   +5 more
doaj   +1 more source

Hanks-Type Serine/Threonine Protein Kinases and Phosphatases in Bacteria: Roles in Signaling and Adaptation to Various Environments [PDF]

, 2018
Reversible phosphorylation is a key mechanism that regulates many cellular processes in prokaryotes and eukaryotes. In prokaryotes, signal transduction includes two-component signaling systems, which involve a membrane sensor histidine kinase and a ...
Janczarek, Monika, Karaś, Magdalena, Lipa, Paulina, Vinardell González, José María   +3 more
core   +1 more source

Broadband, Flexible, Skin‐Compatible Carbon Dots/Graphene Photodetectors for Wearable Applications

Advanced Functional Materials, EarlyView.
Broadband, flexible photodetectors integrating nitrogen‐rich carbon dots with single‐layer graphene on plastic substrates are demonstrated. A biocompatible chitosan–glycerol electrolyte enables efficient low‐voltage gating and on‐skin operation. The devices exhibit ultraviolet‐to‐near‐infrared response, mechanical robustness under bending, and verified
Nouha Loudhaief, Petr Rozhin, Ilaria Bertuol, Ali Raza, Leonardo Viti, Subhankar Roy, Enrico Cavarzerani, Luca Sbuelz, Matteo Brilli, Andrea Serinolli, Jacopo Nicoletti, Riccardo Piccoli, Sebastián Castilla, Simone Dal Zilio, Enrique Rodríguez‐Castellón, Miriam Serena Vitiello, Maurizio Selva, Flavio Rizzolio, Alvise Perosa, Giovanni Antonio Salvatore, Domenico De Fazio   +20 more
wiley   +1 more source