Results 51 to 60 of about 10,340,542 (292)

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Team Cohesion And Sport Performance

مجلة العلوم و التكنولوجية للنشاطات البدنية و الرياضية, 2019
The sports team is a place where relationships are made and broken, sometimes improving the efficiency of the team, other times are reducing it. The coaches translate this state by several notions namely identity, team spirit, complicity, cooperation or
Nacer-eddine Cherif , Badreddine Dassa
doaj  

International Online Graduate Students’ Perceptions of CoI

EURODL, 2020
With the current issue of student retention and attrition as a major aspect of online education, this interpretivist qualitative case study sought to determine whether online facilitators and online student-to-student relationships affect online graduate
Charmaine Bissessar, Debra Black, Mehraz Boolaky   +2 more
doaj   +1 more source

Encuesta sobre Conflicto y Cohesion Social en Chile 2014

The Survey on Conflict and Social Cohesion in Chile (ENACOES 2014) seeks to contribute to the understanding of beliefs, attitudes, and perceptions towards the different dimensions of coexistence and conflict present in Chilean ...
Reproducible Research, Centre for Social Conflict and Cohesion Studies COES
core   +1 more source

Moving on from ‘anti-racism’? Understandings of ‘community cohesion’ held by youth workers [PDF]

, 2007
‘Community Cohesion’, and the apparent lack of it, was rapidly offered as the explanation for the 2001 disturbances across northern England, and has since become a cornerstone of government approaches to race relations policy.
Thomas, Paul, Thomas, Paul; id_orcid
core   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Revealing the economic consequences of group cohesion

, 2017
We introduce the concept of "group cohesion" to capture the economic consequences of ubiquitous social relationships in group production. We measure group cohesion, adapting the "oneness scale" from psychology.
Starmer, Chris, Tufano, Fabio, Gächter, Simon   +2 more
core   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

Structural equation modeling of collective decision-making's impact on group cohesion [PDF]

International Journal of Human Capital in Urban Management
BACKGROUND AND OBJECTIVES: Cohesion is one of the most important factors in the sustainability of social relationships and organizational success. Evidence shows that many companies and organizations have failed or disappeared due to a lack of cohesion ...
S. Mirbagheri, A. Rafiei Atani, M. Parsanejad, R. Jafari   +3 more
doaj   +1 more source