Results 81 to 90 of about 4,463,683 (330)
FEBS Letters, EarlyView.In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley +1 more source
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Group Duties Without Decision-Making Procedures
Journal of Social Ontology, 2022 Stephanie Collins’ Group Duties offers interesting new arguments and brings together numerous interconnected issues that have hitherto been treated separately.
Gunnar Björnsson
doaj
Approaches to assess the group consensus in Yes-or-No type experts' group decision making
Agricultural Economics (AGRICECON), 2010 Group consensus indicators provide an important insight and information about how to combine a group of expert judgments. This paper is concerned with the development of a set of indicators to be used in analyzing the group consensus in evaluating Yes-or-
Shady ALY, Ivan VRANA
doaj +1 more source
The role and implications of mammalian cellular circadian entrainment
FEBS Letters, EarlyView.At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
International Journal of Disaster Risk Science, 2020 In emergency decision making (EDM), it is necessary to generate an effective alternative quickly. Case-based reasoning (CBR) has been applied to EDM; however, choosing the most suitable case from a set of similar cases after case retrieval remains ...
Jing Zheng +3 more
doaj +1 more source
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
AHP-Group Decision Making Based on Consistency
Mathematics, 2019 The Precise consistency consensus matrix (PCCM) is a consensus matrix for AHP-group decision making in which the value of each entry belongs, simultaneously, to all the individual consistency stability intervals.
Juan Aguarón +3 more
doaj +1 more source
Cooperation and conflict in family decision making [PDF]
, 2008 This study addresses the family dynamics of the decision making process, in particular the issues of cooperation and conflict, in both two parent and lone parent families.
Catterall, M., Hamilton, K.L.
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