Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng +8 more
wiley +1 more source
Identification of knowledge, behavior and health application needs for cardiovascular disease prevention in young women: An interview and focus group discussion study in Makassar city. [PDF]
Rachman I +6 more
europepmc +1 more source
The potential for effective reasoning guides children's preference for small group discussion over crowdsourcing. [PDF]
Richardson E, Keil FC.
europepmc +1 more source
Discussion of the Draft Strategy Document Initiatives: Discussion Document
The CERN Council, in a special meeting held the 14th of July 2006 in Lisbon, agreed on the European strategy for particle physics. A "discussion document", assembled by the Preparatory Group of the Strategy Group using the outcome of the Zeuthen Workshop,
CERN. Geneva. Council Strategy Group
core
Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park +8 more
wiley +1 more source
Comparing the impact of video feedback and group discussion on patient education performance among medical interns: a randomized controlled trial. [PDF]
Managheb SE +4 more
europepmc +1 more source
I'm No Superman: fostering physician resilience through guided group discussion of Scrubs. [PDF]
Holtzclaw A, Ellis J, Colombo C.
europepmc +1 more source
DNA ligase LigE increases bacterial transformation with damaged extracellular DNA
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan +4 more
wiley +1 more source
Designing Digital Mental Health Interventions to Meet the Needs of Older Adolescents: Qualitative Interview and Group Discussion Study. [PDF]
Kornfield R +8 more
europepmc +1 more source

