Results 181 to 190 of about 17,551,584 (286)

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Designing Digital Mental Health Interventions to Meet the Needs of Older Adolescents: Qualitative Interview and Group Discussion Study. [PDF]

JMIR Form Res
Kornfield R, Popowski SA, Tack E, Svoboda J, Herrera M, Nguyen T, Knapp AA, Mohr DC, Meyerhoff J.   +8 more
europepmc   +1 more source

The effect of professional teaching videos induction and online focused group discussion on the development of teacher competences. [PDF]

Educ Res Policy Pract, 2022
Mohamadi Zenouzagh Z.
europepmc   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Trainers' Perspectives Towards Digital Mental Health Training for Primary Care Providers: Insights from Focused Group Discussion. [PDF]

Indian J Psychol Med
Mullerpattan GS, Pearala N, Shetty T, Hegde PR, Patley R, Manjunatha N, Math SB, Kumar CN.   +7 more
europepmc   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Multistakeholder scientific advice for medicinal products used in combination with a medical device or a companion diagnostic in the EU-summary of a Focus group discussion. [PDF]

Front Med (Lausanne)
Aarum S, Popp C, Hunter A, Skvarc M, Reischl I, Zander H, Zinserling J, van Leeuwen P, Sutch J, Chesworth T, Kapeller E, Emmendoerffer A, Gravanis I, Bouygues C, Vincenzi C, Berntgen M.   +15 more
europepmc   +1 more source

Addressing Oral Health Disparities of a Tribal Population Through a Combined Implementation of Focus Group Discussion, Mobile Technology Networking, and Creating a Supportive Environment: A Prospective Study. [PDF]

Cureus, 2023
Kumari M, Sharma S, Raj A, Jha A, Shivakumar S, Kumar A.   +5 more
europepmc   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Evaluating the impact of video-only, video with group discussion, and collaborative 360VR on abdominal examination training for first-semester medical students and medicine with industrial specialization. [PDF]

BMC Med Educ
Krishnasamy R, Hansen MP, Schmidt Arenholt LT, Davidsen JG.   +3 more
europepmc   +1 more source