Results 81 to 90 of about 20,463,524 (267)

Group-equivariant diffusion models for lattice field theory

open access: yesJournal of High Energy Physics
Near the critical point, Markov Chain Monte Carlo simulations of lattice quantum field theories become increasingly inefficient due to critical slowing down.
Octavio Vega   +3 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Conformal spacelike-timelike correspondence in QCD

open access: yesJournal of High Energy Physics, 2018
This paper is a study of a spacelike-timelike conformal correspondence in QCD. When the times at vertices are fixed in an A + = 0 gauge calculation the distribution of gluons in a highly virtual decay have an exact correspondence with the gluons in the ...
A. H. Mueller
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Group field theories for all loop quantum gravity

open access: yesNew Journal of Physics, 2015
Group field theories represent a second quantized reformulation of the loop quantum gravity state space and a completion of the spin foam formalism. States of the canonical theory, in the traditional continuum setting, have support on graphs of arbitrary
Daniele Oriti   +2 more
doaj   +1 more source

Seeking fixed points in multiple coupling scalar theories in the ε expansion

open access: yesJournal of High Energy Physics, 2018
Fixed points for scalar theories in 4 − ε, 6 − ε and 3 − ε dimensions are discussed. It is shown how a large range of known fixed points for the four dimensional case can be obtained by using a general framework with two couplings.
Hugh Osborn, Andreas Stergiou
doaj   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

open access: yesMolecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic   +15 more
wiley   +1 more source

Advanced Concepts in Particle and Field Theory [PDF]

open access: yes, 2016
Uniting the usually distinct areas of particle physics and quantum field theory, gravity and general relativity, this expansive and comprehensive textbook of fundamental and theoretical physics describes the quest to consolidate the elementary particles ...
Hübsch, Tristan
core   +1 more source

Bootstrapping hypercubic and hypertetrahedral theories in three dimensions

open access: yesJournal of High Energy Physics, 2018
There are three generalizations of the Platonic solids that exist in all dimensions, namely the hypertetrahedron, the hypercube, and the hyperoctahedron, with the latter two being dual.
Andreas Stergiou
doaj   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

open access: yesMolecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee   +3 more
wiley   +1 more source

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