Results 81 to 90 of about 488,642 (308)
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
New Journal of Physics, 2014 In the context of group field theory condensate cosmology, we clarify the extraction of cosmological variables from the microscopic quantum gravity degrees of freedom.
Steffen Gielen, Daniele Oriti
doaj +1 more source
Relational observables in group field theory
Classical and Quantum GravityAbstract We construct relational observables in group field theory (GFT) in terms of covariant positive operator-valued measures (POVMs), using techniques developed in the context of quantum reference frames (QRFs). We focus on matter QRFs; this can be generalized to other types of frames within the same POVM-based framework.
Luca Marchetti, Edward Wilson-Ewing
openaire +3 more sources
Effective Hamiltonian constraint from group field theory
, 2011 Spinfoam models provide a covariant formulation of the dynamics of loop quantum gravity. They are non-perturbatively defined in the group field theory (GFT) framework: the GFT partition function defines the sum of spinfoam transition amplitudes over all ...
James P Ryan +5 more
core +1 more source
Multi-loop open string amplitudes and their field theory limit [PDF]
, 2013 JHEP is an open-access journal funded by SCOAP3 and licensed under CC BY 4.0This work was supported by STFC (Grant ST/J000469/1, ‘String theory, gauge theory & duality’) and by MIUR (Italy) under contracts 2006020509 004 and 2010YJ2NYW ...
Sciuto, S +3 more
core +1 more source
Renormalizing Open Quantum Field Theories
, 2022 International audienceThe functional renormalization group flow of a scalar field theory with quartic couplings and a sharp spatial momentum cutoff is presented in four-dimensional Minkowski space-time for the bare action by retaining the entanglement of
Polonyi, J. +3 more
core +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Properties of the є-expansion, Lagrange inversion and associahedra and the O (1) model
Journal of High Energy Physics, 2020 We discuss properties of the є-expansion in d = 4 − є dimensions. Using Lagrange inversion we write down an exact expression for the value of the Wilson-Fisher fixed point coupling order by order in є in terms of the beta function coefficients.
Thomas A. Ryttov
doaj +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Gibbsing spacetime: a group field theory approach to equilibrium in quantum gravity
New Journal of Physics, 2018 The symmetries, subtle nature of observables, and lack of a preferred notion of time evolution all make defining a quantum statistical mechanics of general relativity difficult.
Hal M Haggard
doaj +1 more source