Results 131 to 140 of about 388,991 (266)

Art's hidden topology: A window into human perception. [PDF]

PLoS Comput Biol
Dmitruk E, Bajno B, Kot L, Dreszer J, Bałaj B, Ratajczak E, Hajnowski M, Janik RA, Kuś M, Kadir SN, Rogala J.   +10 more
europepmc   +1 more source

Harnessing MDM2‐Mediated Targeted Degradation of Transcriptional and Epigenetic Machinery to Disrupt Oncogenic Addictions in Pediatric Sarcoma

Advanced Science, EarlyView.
MDM2 dependency in pediatric sarcomas is driven by a novel p53‐independent oncogenic cistrome alongside canonical p53 pathway suppression. This study introduces MDM2‐recruiting transcriptional and epigenetic machinery degraders (MDM2‐TEMADs) as a novel precision oncology modality.
Jiawei Zhou, Xian Guan, Nan Li, Ying Zhang, Long Xie, Xingze Huang, Zhipeng Zhu, Zhuolin Ren, Xiaoyan Yu, Hanjun Guo, Yuanfang Wu, Lin Ma, Suya Zheng, Jingyao Zhang, Jiyang Liu, Victor Kuanmin Lee, Wenhao Chen, H. Phillip Koeffler, Jinhu Wang, Xin Han, Ye Chen, Liang Xu   +21 more
wiley   +1 more source

What makes a mycoparasite? Candidate effectors from fungi that parasitize other fungi exhibit structural homology to those of fungal plant pathogens. [PDF]

Fungal Biol Biotechnol
Sotiropoulos AG, Heuberger M, Wicker T, Kiss L.   +3 more
europepmc   +1 more source

Quandle homology and relative group homology

We introduce a chain map from quandle homology to relative group homology, and construct several quandle cocycles through the chain map. We also relate this chain map to triangulations of Seifert (hyper)surfaces of 1- and 2-dimensional links.
openaire   +2 more sources

Radiotherapy Enhances the Oncolytic Efficacy of the Novel Oncolytic Herpesvirus VG161 and Amplifies Its Antitumor Immunity in Breast Cancer

Advanced Science, EarlyView.
RT promotes VG161 replication in BC and its immunostimulatory transgenes expression, which is mediated by the upregulation of GADD34 and HVEM caused by RT. The combination therapy with VG161 and RT increases the abundances of tumor‐infiltrating lymphocytes and elicits potent systemic antitumor immunity, thereby effectively inhibiting local tumors and ...
Lijuan Lyu, Ming Yi, Ji Chen, Zeda Zhao, Ruocen Liao, Yingnan Wang, Shengtao Hu, Jun Ding, Ronghua Zhao, William Jia, Yinan Shen, Yongchang Wei, Kongming Wu, Zhijun Dai   +13 more
wiley   +1 more source

On the first homology of automorphism groups of manifolds with geometric structures

Open Mathematics, 2005
Abe Kōjun, Fukui Kazuhiko
doaj   +1 more source

Positive curvature conditions on contractible manifolds. [PDF]

Math Ann
Sweeney P.
europepmc   +1 more source

Disruption of the SNRPF–DDX24–E2F4 Feedback Loop Uncouples Splicing and Transcriptional Regulation to Suppress Ovarian Cancer Progression

Advanced Science, EarlyView.
This study identifies SNRPF as a critical oncogenic driver in ovarian cancer. By regulating a self‐sustaining SNRPF–DDX24–E2F4 feedback loop through intron retention and nonsense‐mediated decay, SNRPF couples RNA splicing with transcriptional regulation to promote tumor progression.
Yingwei Li, Zhongshao Chen, Qianqian Gao, Yuehan Gao, Ning Yang   +4 more
wiley   +1 more source

Possible Triggering of Molecular Mimicry by Environmental Pollution. [PDF]

Biology (Basel)
Mishina S, Adams B, Uhal B, Liang Y.
europepmc   +1 more source

ON THE HOMOLOGY OF SPINOR GROUPS

Memoirs of the Faculty of Science, Kyushu University. Series A, Mathematics, 1955
openaire   +3 more sources