Results 101 to 110 of about 49,487 (207)
Advanced Science, Volume 13, Issue 1, 5 January 2026.Our study reveals a novel mechanism by which palmitoylation regulates ferroptosis and enzalutamide resistance in prostate cancer. Under enzalutamide resistance, the FOXA1/CXXC5/TET2 complex induces aberrant upregulation of ZDHHC2, which subsequently suppresses ferroptosis by mediating S‐palmitoylation of USP19 and degradation of ACSL4 protein in CRPC ...
Shuai Shao +10 more
wiley +1 more source
Cross‐Species Insights Into Gamma Herpesvirus Transcriptomes: Long‐Read and Multi‐Omics Perspectives
Journal of Medical Virology, Volume 98, Issue 1, January 2026.ABSTRACT Comparative transcriptome analyses of gamma herpesviruses have been revolutionized by long‐read sequencing and integrative multi‐omics approaches, enabling unprecedented resolution of viral gene expression. Cross‐species studies of Kaposi's sarcoma‐associated herpesvirus (KSHV), Epstein–Barr virus (EBV), and murine gamma herpesvirus 68 (MHV68)
Ritu Shekhar +4 more
wiley +1 more source
Functional Relevance of CASP16 Nucleic Acid Predictions as Evaluated by Structure Providers
Proteins: Structure, Function, and Bioinformatics, Volume 94, Issue 1, Page 51-78, January 2026.ABSTRACT Accurate biomolecular structure prediction enables the prediction of mutational effects, the speculation of function based on predicted structural homology, the analysis of ligand binding modes, experimental model building, and many other applications.
Rachael C. Kretsch +32 more
wiley +1 more source
The RNA‐Puzzles Assessments of RNA‐Only Targets in CASP16
Proteins: Structure, Function, and Bioinformatics, Volume 94, Issue 1, Page 218-229, January 2026.ABSTRACT RNA‐Puzzles was launched in 2011 as a collaborative effort dedicated to advancing and improving RNA 3D structure prediction. The automatic evaluation protocols for comparisons between prediction and experiment developed within RNA‐Puzzles are applied to the 2024 CASP16 competition.
Eric Westhof +3 more
wiley +1 more source
British Journal of Haematology, Volume 208, Issue 1, Page 116-128, January 2026.VEXAS syndrome is a late‐onset inflammatory disorder with rheumatological and haematological features. Epidemiological studies of VEXAS syndrome so far have been limited. Analysis of various UK cohorts estimates the incidence of VEXAS to be 1.51/100 000, or 171 new cases in the population of men over the age of 50 who are being investigated for myeloid
Ana Martinez Rodriguez +15 more
wiley +1 more source
The Spliceosomal Protein Prp8 Stabilizes A Compact Conformation Of The U2-U6 Complex [PDF]
, 2012 The spliceosome is a large, RNA-protein complex that catalyzes pre-mRNA splicing during mRNA maturation. The RNA components (small nuclear RNA; snRNAs) of the spliceosome have been well studied and are believed to be involved in the splicing catalysis ...
Subasinghe, Subasinghe Appuhamilage Lemintha Imali
core +1 more source
Evolutionary Applications, Volume 19, Issue 1, January 2026.ABSTRACT Ultraconserved elements (UCEs) have emerged as a powerful tool for resolving deep evolutionary relationships due to their low DNA quality requirements and broad taxonomic applicability. While their utility for intraspecific and shallow‐divergence studies is growing, only a few studies have explored their performance in marine taxa, some of ...
Yi‐Xuan Li +6 more
wiley +1 more source
Regulation of CNS and motor axon guidance in Drosophila by the receptor tyrosine phosphatase DPTP52F [PDF]
, 2001 Receptor-linked protein tyrosine phosphatases (RPTPs) regulate axon guidance and synaptogenesis in Drosophila embryos and larvae. We describe DPTP52F, the sixth RPTP to be discovered in Drosophila.
Knirr, Matthias +3 more
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Experimental Dermatology, Volume 35, Issue 1, January 2026.ABSTRACT Abnormal NF‐κB activity has been previously implicated in a range of immune‐mediated disorders. Here, we aimed to elucidate the genetic basis underlying the co‐occurrence of vitiligo, Addison's disease and granuloma annulare in a 43‐year‐old woman.
Kiril Malovitski +13 more
wiley +1 more source
Polymorphisms in the WNK1 gene are asociated with blood pressure variation and urinary potassium excretion [PDF]
, 2009 WNK1 - a serine/threonine kinase involved in electrolyte homeostasis and blood pressure (BP) control - is an excellent candidate gene for essential hypertension (EH). We and others have previously reported association between WNK1 and BP variation. Using
Brown, M +34 more
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