Folding of group I introns from bacteriophage T4 involves internalization of the catalytic core. [PDF]
Timothy S. Heuer+4 more
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Protein phosphatase beta, a putative type-2A protein phosphatase from the human malaria parasite Plasmodium falciparum. [PDF]
Protein phosphatases play a critical role in the regulation of the eukaryotic cell cycle and signal transduction. A putative protein serine/threonine phosphatase gene has been isolated from the human malaria parasite Plasmodium falciparum.
Arndt K. T.+32 more
core +1 more source
Long range correlations in DNA sequences [PDF]
The so called long range correlation properties of DNA sequences are studied using the variance analyses of the density distribution of a single or a group of nucleotides in a model independent way. This new method which was suggested earlier has been applied to extract slope parameters that characterize the correlation properties for several intron ...
arxiv
Pentamidine inhibits catalytic activity of group I intron Ca.LSU by altering RNA folding [PDF]
Yi Zhang
openalex +1 more source
Integrating experimental feedback improves generative models for biological sequences [PDF]
Generative probabilistic models have shown promise in designing artificial RNA and protein sequences but often suffer from high rates of false positives, where sequences predicted as functional fail experimental validation. To address this critical limitation, we explore the impact of reintegrating experimental feedback into the model design process ...
arxiv
Positioning Crenarchaeal tRNA-Introns [PDF]
We precisely position a noncanonical intron in the odd second copy of tRNAAsp(GTC) gene in the newly sequenced crenarchaea S.acidocaldarius. The uniform assortment of some features from normal aspartate tDNA and some from those corresponding to non-standard amino acids conduce us to conjecture it to be a novel tRNA gene, probably coding for a modified ...
arxiv
A tyrosyl-tRNA synthetase binds specifically to the group I intron catalytic core. [PDF]
Qiang Guo, Alan M. Lambowitz
openalex +1 more source
Functional Identification of Ligands for a Catalytic Metal Ion in Group I Introns [PDF]
Marcello Forconi+4 more
openalex +1 more source
One RNA plays three roles to provide catalytic activity to a group I intron lacking an endogenous internal guide sequence [PDF]
Nilesh Vaidya, Niles Lehman
openalex +1 more source
Ribozymes: the characteristics and properties of catalytic RNAs [PDF]
Ribozymes, or catalytic RNAs, were discovered a little more than 15 years ago. They are found in the organelles of plants and lower eukaryotes, in amphibians, in prokaryotes, in bacteriophages, and in viroids and satellite viruses that infect plants.
Tanner, N. Kyle
core