Results 191 to 200 of about 775,451 (311)

Shennong 1 Chicken 40K Liquid Chip: Advancing Genetic Research in Chinese Indigenous Chickens

open access: yesAnimal Research and One Health, EarlyView.
Based on comprehensive genomic data of Chinese indigenous chickens, we developed a specialized genotyping array for this population. Comparative analyses with published mainstream arrays and evaluations, including genetic assessment of diverse chicken types and gene mining analyses, demonstrated its superior applicability to Chinese indigenous chickens.
Chaoqun Gao   +14 more
wiley   +1 more source

Retrotransposition of a yeast group II intron occurs by reverse splicing directly into ectopic DNA sites

open access: green, 2001
Lorna M. Dickson   +5 more
openalex   +1 more source

Prevalence of Group II Introns in Phage Genomes

open access: yes
AbstractAlthough bacteriophage genomes are under strong selective pressure for high coding density, they are still frequently invaded by mobile genetic elements (MGEs). Group II introns are MGEs that reduce host burden by autocatalytically splicing out of RNA before translation.
Liana N. Merk   +2 more
openaire   +1 more source

Technological Innovations and Applications of Spatial Transcriptomics in Livestock and Poultry Research

open access: yesAnimal Research and One Health, EarlyView.
The paper is divided into three main sections: a review of the development of spatial transcriptomics technology, its applications in livestock and poultry research, and its future prospects. This article provides an overview of the current state of spatial transcriptomics in animal research, exploring its integration with multiomics technologies as ...
Mingyu Wang   +5 more
wiley   +1 more source

Alu Overexpression Leads to an Increased Double‐stranded RNA Signature in Dermatomyositis

open access: yesArthritis &Rheumatology, Accepted Article.
Objective Dermatomyositis is an autoimmune condition characterized by a high interferon signature of unknown etiology. Because coding sequences constitute <1.2% of our genomes, there is a need to explore the role of the non‐coding genome in disease pathogenesis.
Rayan Najjar   +2 more
wiley   +1 more source

Comprehensive Mapping of Functional Enhancers in Chinese Hamster Ovary Cells

open access: yesBiotechnology and Bioengineering, EarlyView.
In this study, the authors identified regions with enhancer activity in the CHO cell genome using genome‐wide and targeted STARR‐seq. The analysis revealed thousands of newly identified enhancer sequences, where some of the most active sequences could drive transgene expression at levels similar to or higher than strong viral enhancers.
María Santos   +9 more
wiley   +1 more source

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