Results 201 to 210 of about 185,672 (304)

Structural basis for the second step of group II intron splicing. [PDF]

Nat Commun, 2018
Chan RT, Peters JK, Robart AR, Wiryaman T, Rajashankar KR, Toor N.   +5 more
europepmc   +1 more source

Behavioral and epileptic phenotypes in a CHD2‐related developmental delay model

Epilepsia, EarlyView.
Abstract Objective Heterozygous loss‐of‐function mutations in the CHD2 gene, encoding chromodomain helicase DNA‐binding protein 2, are associated with severe childhood onset epilepsy, global developmental delay, and autistic features. Animal models that accurately recapitulate human phenotypes are crucial for understanding rare neurodevelopmental ...
Anat Mavashov, Shaked Turk, Yael Sarusi, Marina Brusel, Rotem Ben Tov Perry, Shir Quinn, Yael Almog, Karni Vilian, Mor Yam, Igor Ulitsky, Moran Rubinstein   +10 more
wiley   +1 more source

Group II Intron RNPs and Reverse Transcriptases: From Retroelements to Research Tools. [PDF]

Cold Spring Harb Perspect Biol, 2019
Belfort M, Lambowitz AM.
europepmc   +1 more source

Genetic epilepsies with myoclonic seizures: Mechanisms and syndromes

Epilepsia Open, EarlyView.
Abstract Genetic epilepsy with myoclonic seizures encompasses a heterogeneous spectrum of conditions, ranging from benign and self‐limiting forms to severe, progressive disorders. While their causes are diverse, a significant proportion stems from genetic abnormalities.
Antonietta Coppola, Marica Rubino, Antonella Riva, Pasquale Striano   +3 more
wiley   +1 more source

Nuclear expression of a group II intron is consistent with spliceosomal intron ancestry [PDF]

, 2010
Venkata R. Chalamcharla, M. Joan Curcio, Marlene Belfort   +2 more
openalex   +1 more source

Structural accommodations accompanying splicing of a group II intron RNP. [PDF]

Nucleic Acids Res, 2018
Dong X, Ranganathan S, Qu G, Piazza CL, Belfort M.   +4 more
europepmc   +1 more source

Molecular Mechanism of Mulberrin Regulating Lipid Metabolism Homeostasis Based on the Gut–Liver Axis Fiaf/AMPK Signaling Pathway

Food Frontiers, EarlyView.
The molecular mechanism for mulberrin regulating lipid metabolism homeostasis. ABSTRACT Lipid metabolism disorders and the induced metabolic diseases have risen to become one of the primary public health issues. Our preliminary experimental results confirmed that mulberry leaf flavonoid extract exhibited efficacy in lipid metabolism regulation; the ...
Qian Li, Daorui Pang, Erna Li, Dongxu Xing, Fan Liu, Li Wang, Yuxiao Zou   +6 more
wiley   +1 more source

Relevance of the Branch Point Adenosine, Coordination Loop, and 3′ Exon Binding Site for in Vivo Excision of the Sinorhizobium meliloti Group II Intron RmInt1 [PDF]

, 2011
María Dolores Molina-Sánchez, Antonio Barrientos‐Durán, Nicolás Toro   +2 more
openalex   +1 more source

Structural Insights into the Mechanism of Group II Intron Splicing. [PDF]

Trends Biochem Sci, 2017
Zhao C, Pyle AM.
europepmc   +1 more source

Evolutionary patterns and structural divergence of CENH3 in legumes: Implications for haploid induction breeding

Grassland Research, EarlyView.
From structure to application: evolutionary insights and genome editing strategies for CENH3‐mediated haploid induction in legumes. Abstract Background The centromeric histone variant CENH3 is crucial for chromosome segregation and haploid induction in plants, yet its evolutionary patterns in legumes remain poorly characterized. Methods We investigated
Jialiang Zhou, Kai Wang
wiley   +1 more source