Results 211 to 220 of about 757,384 (292)
ABSTRACT Background Adenoid cystic carcinoma (ACC) is an aggressive therapy‐resistant head and neck cancer with a high frequency of local recurrences and distant metastases. Activation of the MYB gene, encoding an oncogenic master transcription factor, is the key genomic hallmark of ACC and a potential therapeutic target. Here, we have investigated the
Fredrik Jäwert+5 more
wiley +1 more source
Principles of 3′ splice site selection and alternative splicing for an unusual group II intron from Bacillus anthracis [PDF]
Aaron R. Robart+3 more
openalex +1 more source
High-affinity binding site for a group II intron-encoded reverse transcriptase/maturase within a stem–loop structure in the intron RNA [PDF]
Kazuo Watanabe, Alan M. Lambowitz
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CRS1, a Chloroplast Group II Intron Splicing Factor, Promotes Intron Folding through Specific Interactions with Two Intron Domains [PDF]
Oren Ostersetzer+3 more
openalex +1 more source
An obligate intermediate along the slow folding pathway of a group II intron ribozyme [PDF]
Linhui Julie Su
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What's new? Tumor necrosis factor (TNF) can promote tumor resistance to immune checkpoint inhibitors (ICIs), which are now the standard treatment for advanced melanoma patients. Here, in an advanced melanoma patient cohort, TNF was investigated for a possible predictive relationship with ICI response. Assessments show that after 12 weeks of ICI therapy,
Mathieu Virazels+18 more
wiley +1 more source
Unusual Group II Introns in Bacteria of the Bacillus cereus Group [PDF]
Nicolas J. Tourasse+3 more
openalex +1 more source
Abstract Objective In the present study, a bidirectional two‐sample Mendelian randomization approach was utilized to explore potential causal relationships between mitochondrial DNA copy number (mtDNA‐CN) and ovary‐related reproductive disorders (ORRDs), including ovarian dysfunction, ovarian cyst, polycystic ovary syndrome (PCOS), premature ovarian ...
Ke Peng+4 more
wiley +1 more source