Database for bacterial group II introns [PDF]
Nucleic Acids Research, 2011 The Database for Bacterial Group II Introns (http://webapps2.ucalgary.ca/~groupii/index.html#) provides a catalogue of full-length, non-redundant group II introns present in bacterial DNA sequences in GenBank. The website is divided into three sections.
Li Wu +9 more
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The circle to lariat ratio of the Ll.LtrB group II intron from Lactococcus lactis is greatly influenced by a variety of biological determinants in vivo. [PDF]
PLoS ONE, 2020 Bacterial group II introns mostly behave as versatile retromobile genetic elements going through distinct cycles of gain and loss. These large RNA molecules are also ribozymes splicing autocatalytically from their interrupted pre-mRNA transcripts by two ...
Caroline Monat, Benoit Cousineau
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Group II Intron RNPs and Reverse Transcriptases: From Retroelements to Research Tools. [PDF]
Cold Spring Harb Perspect Biol, 2019 SUMMARYGroup II introns, self-splicing retrotransposons, serve as both targets of investigation into their structure, splicing, and retromobility and a source of tools for genome editing and RNA analysis.
Belfort M, Lambowitz AM.
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An ultraprocessive, accurate reverse transcriptase encoded by a metazoan group II intron. [PDF]
RNA, 2018 Group II introns and non-LTR retrotransposons encode a phylogenetically related family of highly processive reverse transcriptases (RTs) that are essential for mobility and persistence of these retroelements. Recent crystallographic studies on members of
Zhao C, Liu F, Pyle AM.
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Group II intron protein localization and insertion sites are affected by polyphosphate. [PDF]
PLoS Biology, 2008 Mobile group II introns consist of a catalytic intron RNA and an intron-encoded protein with reverse transcriptase activity, which act together in a ribonucleoprotein particle to promote DNA integration during intron mobility.
Junhua Zhao +5 more
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Structure of a group II intron in complex with its reverse transcriptase. [PDF]
Nat Struct Mol Biol, 2016 Bacterial group II introns are large catalytic RNAs related to nuclear spliceosomal introns and eukaryotic retrotransposons. They self-splice to yield mature RNA, and integrate into DNA as retroelements.
Qu G +7 more
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Group II introns in the bacterial world [PDF]
Molecular Microbiology, 2000 Group II introns are large catalytic RNA molecules that act as mobile genetic elements. They were initially identified in the organelle genomes of lower eukaryotes and plants, and it has been suggested that they are the progenitors of nuclear spliceosomal introns.
Francisco Martı́nez-Abarca +1 more
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Optimal molecular crowding accelerates group II intron folding and maximizes catalysis. [PDF]
Proc Natl Acad Sci U S A, 2018 Significance Biological processes take place in living cells and have adapted to environmental conditions such as temperature, salt concentration, and high-density cellular contents.
Paudel BP +4 more
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Group II intron-anchored gene deletion in Clostridium. [PDF]
PLoS ONE, 2011 Clostridium plays an important role in commercial and medical use, for which targeted gene deletion is difficult. We proposed an intron-anchored gene deletion approach for Clostridium, which combines the advantage of the group II intron "ClosTron" system
Kaizhi Jia +3 more
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Template-switching mechanism of a group II intron-encoded reverse transcriptase and its implications for biological function and RNA-Seq. [PDF]
J Biol Chem, 2019 The reverse transcriptases (RTs) encoded by mobile group II introns and other non-LTR retroelements differ from retroviral RTs in being able to template-switch efficiently from the 5′ end of one template to the 3′ end of another with little or no ...
Lentzsch AM +3 more
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