Results 21 to 30 of about 364,363 (199)

The Agaricus bisporus cox1 gene: the longest mitochondrial gene and the largest reservoir of mitochondrial group i introns. [PDF]

open access: yesPLoS ONE, 2010
In eukaryotes, introns are located in nuclear and organelle genes from several kingdoms. Large introns (up to 5 kbp) are frequent in mitochondrial genomes of plant and fungi but scarce in Metazoa, even if these organisms are grouped with fungi among the ...
Cyril Férandon   +5 more
doaj   +5 more sources

Visualizing group II intron dynamics between the first and second steps of splicing [PDF]

open access: yesNature Communications, 2020
Group II introns are self-splicing ribozymes. Here, the authors employ enzymatic assay, X-ray crystallography and molecular dynamics simulations to show that protonation of the group II intron catalytic triad plays an important role for the transition ...
Jacopo Manigrasso   +7 more
doaj   +2 more sources

Multiple physical forms of excised group II intron RNAs in wheat mitochondria [PDF]

open access: gold, 2006
Plant mitochondrial group II introns do not all possess hallmark ribozymic features such as the bulged adenosine involved in lariat formation. To gain insight into their splicing pathways, we have examined the physical form of excised introns in ...
Jennifer Li‐Pook‐Than, Linda Bonen
openalex   +4 more sources

Organellar Introns in Fungi, Algae, and Plants

open access: yesCells, 2021
Introns are ubiquitous in eukaryotic genomes and have long been considered as ‘junk RNA’ but the huge energy expenditure in their transcription, removal, and degradation indicate that they may have functional significance and can offer evolutionary ...
Jigeesha Mukhopadhyay, Georg Hausner
doaj   +1 more source

Evolution of group II introns [PDF]

open access: yesMobile DNA, 2015
Present in the genomes of bacteria and eukaryotic organelles, group II introns are an ancient class of ribozymes and retroelements that are believed to have been the ancestors of nuclear pre-mRNA introns. Despite long-standing speculation, there is limited understanding about the actual pathway by which group II introns evolved into eukaryotic introns.
Zimmerly, Steven, Semper, Cameron
openaire   +4 more sources

Group II intron and repeat-rich red algal mitochondrial genomes demonstrate the dynamic recent history of autocatalytic RNAs

open access: yesBMC Biology, 2022
Background Group II introns are mobile genetic elements that can insert at specific target sequences, however, their origins are often challenging to reconstruct because of rapid sequence decay following invasion and spread into different sites.
Dongseok Kim   +5 more
doaj   +1 more source

Distinct Expansion of Group II Introns During Evolution of Prokaryotes and Possible Factors Involved in Its Regulation

open access: yesFrontiers in Microbiology, 2022
Group II introns (G2Is) are ribozymes that have retroelement characteristics in prokaryotes. Although G2Is are suggested to have been an important evolutionary factor in the prokaryote-to-eukaryote transition, comprehensive analyses of these introns ...
Masahiro C. Miura   +9 more
doaj   +1 more source

The brown algae Pl.LSU/2 group II intron-encoded protein has functional reverse transcriptase and maturase activities. [PDF]

open access: yesPLoS ONE, 2013
Group II introns are self-splicing mobile elements found in prokaryotes and eukaryotic organelles. These introns propagate by homing into precise genomic locations, following assembly of a ribonucleoprotein complex containing the intron-encoded protein ...
Madeleine Zerbato   +5 more
doaj   +1 more source

Dynamics of group II introns in plant mitogenomes and rickettsial DNA invasions in the mitogenome of Haplopteris ensiformis [PDF]

open access: yes, 2023
The complexity of mitochondrial genomes (mtDNA) in vascular plants is well-known, with factors such as repetitive sequences, variable structural organization, gene synteny decline, high intron content, and RNA editing contributing to their intricate ...
Zumkeller, Simon Maria
core   +1 more source

Structure determination of group II introns [PDF]

open access: yesMethods, 2017
Group II introns are self-splicing catalytic RNAs that are able to excise themselves from pre-mRNAs using a mechanism identical to that utilized by the spliceosome. Both structural and phylogenetic data support the hypothesis that group II introns and the spliceosome share a common ancestor.
Timothy Wiryaman, Navtej Toor
openaire   +5 more sources

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