Structure determination of group II introns [PDF]
Methods, 2017 Group II introns are self-splicing catalytic RNAs that are able to excise themselves from pre-mRNAs using a mechanism identical to that utilized by the spliceosome. Both structural and phylogenetic data support the hypothesis that group II introns and the spliceosome share a common ancestor.
Timothy Wiryaman, Navtej Toor
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BMC Ecology and Evolution, 2023 Group II introns are common in the two endosymbiotic organelle genomes of the plant lineage. Chloroplasts harbor 22 positionally conserved group II introns whereas their occurrence in land plant (embryophyte) mitogenomes is highly variable and specific ...
Simon Zumkeller, Volker Knoop
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Database for bacterial group II introns [PDF]
Nucleic Acids Research, 2011 The Database for Bacterial Group II Introns (http://webapps2.ucalgary.ca/~groupii/index.html#) provides a catalogue of full-length, non-redundant group II introns present in bacterial DNA sequences in GenBank. The website is divided into three sections.
Candales, Manuel A. +9 more
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Unraveling the role of the enigmatic MatK maturase in chloroplast group IIA intron excision
Plant Direct, 2020 Maturases are prokaryotic enzymes that aid self‐excision of introns in precursor RNAs and have evolutionary ties to the nuclear spliceosome. Both the mitochondria and chloroplast, due to their prokaryotic origin, encode a single intron maturase, MatR for
Michelle M. Barthet +2 more
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Group II intron–ribosome association protects intron RNA from degradation [PDF]
RNA, 2013 The influence of the cellular environment on the structures and properties of catalytic RNAs is not well understood, despite great interest in ribozyme function. Here we report on ribosome association of group II introns, which are ribozymes that are important because of their putative ancestry to spliceosomal introns and retrotransposons, their ...
Contreras, Lydia M. +8 more
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Host Factors Influencing the Retrohoming Pathway of Group II Intron RmInt1, Which Has an Intron-Encoded Protein Naturally Devoid of Endonuclease Activity. [PDF]
PLoS ONE, 2016 Bacterial group II introns are self-splicing catalytic RNAs and mobile retroelements that have an open reading frame encoding an intron-encoded protein (IEP) with reverse transcriptase (RT) and RNA splicing or maturase activity.
Rafael Nisa-Martínez +2 more
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Bacterial group II introns generate genetic diversity by circularization and trans-splicing from a population of intron-invaded mRNAs. [PDF]
PLoS Genetics, 2018 Group II introns are ancient retroelements that significantly shaped the origin and evolution of contemporary eukaryotic genomes. These self-splicing ribozymes share a common ancestor with the telomerase enzyme, the spliceosome machinery as well as the ...
Félix LaRoche-Johnston +3 more
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Rapid Targeted Gene Disruption in Bacillus Anthracis [PDF]
, 2013 Anthrax is a zoonotic disease recognized to affect herbivores since Biblical times and has the widest range of susceptible host species of any known pathogen.
Ellington, Andrew +9 more
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The retrohoming of linear group II intron RNAs in Drosophila melanogaster occurs by both DNA ligase 4-dependent and -independent mechanisms. [PDF]
PLoS Genetics, 2012 Mobile group II introns are bacterial retrotransposons that are thought to have invaded early eukaryotes and evolved into introns and retroelements in higher organisms.
Travis B White, Alan M Lambowitz
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Phylogenetic relationships among group II intron ORFs [PDF]
Nucleic Acids Research, 2001 Group II introns are widely believed to have been ancestors of spliceosomal introns, yet little is known about their own evolutionary history. In order to address the evolution of mobile group II introns, we have compiled 71 open reading frames (ORFs) related to group II intron reverse transcriptases and subjected their derived amino acid sequences to ...
S, Zimmerly, G, Hausner, , Wu Xc
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