Circularization pathway of a bacterial group II intron. [PDF]
Nucleic Acids Res, 2016 Group II introns are large RNA enzymes that can excise as lariats, circles or in a linear form through branching, circularization or hydrolysis, respectively. Branching is by far the main and most studied splicing pathway while circularization was mostly overlooked. We previously showed that removal of the branch point A residue from Ll.LtrB, the group
Monat C, Cousineau B.
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Did group II intron proliferation in an endosymbiont-bearing archaeon create eukaryotes? [PDF]
Biology Direct, 2006 Martin & Koonin recently proposed that the eukaryote nucleus evolved as a quality control mechanism to prevent ribosome readthrough into introns. In their scenario, the bacterial ancestor of mitochondria was resident in an archaeal cell, and group II ...
Poole Anthony M
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Analysis of the Roles of the Arabidopsis nMAT2 and PMH2 Proteins Provided with New Insights into the Regulation of Group II Intron Splicing in Land-Plant Mitochondria. [PDF]
Int J Mol Sci, 2017 Plant mitochondria are remarkable with respect to the presence of numerous group II introns which reside in many essential genes. The removal of the organellar introns from the coding genes they interrupt is essential for respiratory functions, and is ...
Zmudjak M +4 more
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Group II Introns: Highly Structured yet Dynamic
CHIMIA, 2023 RNA splicing, the removal of introns and ligation of exons, is a crucial process during mRNA maturation. Group II introns are large ribozymes that self-catalyze their splicing, as well as their transposition.
Esra Ahunbay +2 more
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Identification of a family of group II introns encoding LAGLIDADG ORFs typical of group I introns [PDF]
RNA, 2002 Group I and group II introns are unrelated classes of introns that each encode proteins that facilitate intron splicing and intron mobility. Here we describe a new subfamily of nine introns in fungi that are group II introns but encode LAGLIDADG ORFs typical of group I introns. The introns have fairly standard group IIB1 RNA structures and are inserted
Navtej Toor, Steven Zimmerly
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Cryo-EM Structures of a Group II Intron Reverse Splicing into DNA. [PDF]
Cell, 2019 Haack DB +6 more
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Group II Introns: Flexibility and Repurposing
Frontiers in Molecular Biosciences, 2022 Maria Costa
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Structural Insights into the Mechanism of Group II Intron Splicing. [PDF]
Trends Biochem Sci, 2017 Zhao C, Pyle AM.
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Mutually Exclusive Distribution of IS 1548 and GBSi1, an Active Group II Intron Identified in Human Isolates of Group B Streptococci [PDF]
Journal of Bacteriology, 2001 Margareta Granlund +2 more
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Structure of a Thermostable Group II Intron Reverse Transcriptase with Template-Primer and Its Functional and Evolutionary Implications. [PDF]
Mol Cell, 2017 Stamos JL, Lentzsch AM, Lambowitz AM.
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