Results 61 to 70 of about 775,451 (311)
The retrohoming of linear group II intron RNAs in Drosophila melanogaster occurs by both DNA ligase 4-dependent and -independent mechanisms. [PDF]
PLoS Genetics, 2012 Mobile group II introns are bacterial retrotransposons that are thought to have invaded early eukaryotes and evolved into introns and retroelements in higher organisms.
Travis B White, Alan M Lambowitz
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The trouble with (group II) introns [PDF]
Proceedings of the National Academy of Sciences, 2014 Qu et al. provide new grist for the introns origin mill (1), adding one more chapter to what has become a very long narrative. Back in the day when spliceosomal introns in the protein-coding genes of eukaryotes were still very new to science (1977–1978), some of us argued that—in an evolutionary sense—they were actually very old (2, 3).
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Natural circularly permuted group II introns in bacteria produce RNA circles
iScience, 2021 Summary: Group II self-splicing introns are large structured RNAs that remove themselves from transcripts while simultaneously sealing the resulting gaps.
Adam Roth +4 more
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Using Group II Introns for Attenuating the In Vitro and In Vivo Expression of a Homing Endonuclease. [PDF]
PLoS ONE, 2016 In Chaetomium thermophilum (DSM 1495) within the mitochondrial DNA (mtDNA) small ribosomal subunit (rns) gene a group IIA1 intron interrupts an open reading frame (ORF) encoded within a group I intron (mS1247).
Tuhin Kumar Guha, Georg Hausner
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Frontiers in Plant Science, 2022 Maturases can specifically bind to intron-containing pre-RNAs, folding them into catalytic structures that facilitate intron splicing in vivo. Plants possess four nuclear-encoded maturase-related factors (nMAT1-nMAT4) and some maturases have been shown ...
Kaijian Fan +9 more
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Genetic and biochemical assays reveal a key role for replication restart proteins in group II intron retrohoming. [PDF]
PLoS Genetics, 2013 Mobile group II introns retrohome by an RNP-based mechanism in which the intron RNA reverse splices into a DNA site and is reverse transcribed by the associated intron-encoded protein.
Jun Yao +2 more
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Mechanisms used for genomic proliferation by thermophilic group II introns. [PDF]
PLoS Biology, 2010 Mobile group II introns, which are found in bacterial and organellar genomes, are site-specific retroelements hypothesized to be evolutionary ancestors of spliceosomal introns and retrotransposons in higher organisms.
Georg Mohr +2 more
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RNA: A publication of the RNA Society, 2016 Next-generation RNA-sequencing (RNA-seq) has revolutionized transcriptome profiling, gene expression analysis, and RNA-based diagnostics. Here, we developed a new RNA-seq method that exploits thermostable group II intron reverse transcriptases (TGIRTs ...
Yidan Qin +6 more
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RNA-seq of human reference RNA samples using a thermostable group II intron reverse transcriptase
RNA: A publication of the RNA Society, 2016 Next-generation RNA sequencing (RNA-seq) has revolutionized our ability to analyze transcriptomes. Current RNA-seq methods are highly reproducible, but each has biases resulting from different modes of RNA sample preparation, reverse transcription, and ...
Ryan M. Nottingham +5 more
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Bacterial group II introns: not just splicing [PDF]
FEMS Microbiology Reviews, 2007 Group II introns are both catalytic RNAs (ribozymes) and mobile retroelements that were discovered almost 14 years ago. It has been suggested that eukaryotic mRNA introns might have originated from the group II introns present in the alphaproteobacterial progenitor of the mitochondria.
José I. Jiménez-Zurdo +2 more
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