Identification of the salmonid IL-17A/F1a/b, IL-17A/F2b, IL-17A/F3 and IL-17N genes and analysis of their expression following in vitro stimulation and infection [PDF]
, 2015 Peer ...
Husain, Mansourah +5 more
core +1 more source
The association of group IIB intron with integrons in hypersaline environments
Mobile DNA, 2021 Background Group II introns are mobile genetic elements used as efficient gene targeting tools. They function as both ribozymes and retroelements. Group IIC introns are the only class reported so far to be associated with integrons.
Sarah Sonbol, Rania Siam
doaj +1 more source
Expression of plasma prekallikrein mRNA in human nonhepatic tissues and cell lineages suggests special local functions of the enzyme [PDF]
, 1999 At present it is generally accepted that plasma prekallikrein (PPK) is synthesized in the liver and secreted into the bloodstream. Surprisingly, it has recently been shown that PPK mRNA is present also in RNA from the kidney, adrenal gland and placenta ...
Arnhold, Marianne +4 more
core +1 more source
Polymorphism of the rps16 gene intron in Malus Mill. and related Rosaceae Juss. species
Вавиловский журнал генетики и селекции, 2017 The intron of the chloroplast rps16 gene encoding ribosomal protein 16S belongs to group II introns, which have the capacity to self-splice. The sequence of this intron may be quite polymorphic and is widely used for molecular-genetic studies of ...
M. A. Filyushin, K. V. Boris
doaj +1 more source
The largest reservoir of mitochondrial introns is a relic of an ancestral split gene [PDF]
, 2010 In eukaryotes, introns are located in nuclear and organelle genes from several kingdoms (ref. 1-4). Large introns (0.1 to 5 kbp) are frequent in mitochondrial genomes of plant and fungi (ref.
Cyril Ferandon +5 more
core +1 more source
A Role for Pre-mRNA-PROCESSING PROTEIN 40C in the Control of Growth, Development, and Stress Tolerance in Arabidopsis thaliana [PDF]
, 2019 Because of their sessile nature, plants have adopted varied strategies for growing and reproducing in an ever-changing environment. Control of mRNA levels and pre-mRNA alternative splicing are key regulatory layers that contribute to adjust and ...
Careno, Daniel Alejandro +6 more
core +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Mobile Group II Introns as Ancestral Eukaryotic Elements [PDF]
Trends in Genetics, 2017 The duality of group II introns, capable of carrying out both self-splicing and retromobility reactions, is hypothesized to have played a profound role in the evolution of eukaryotes. These introns likely provided the framework for the emergence of eukaryotic retroelements, spliceosomal introns and other key components of the spliceosome.
Olga, Novikova, Marlene, Belfort
openaire +2 more sources
Did group II intron proliferation in an endosymbiont-bearing archaeon create eukaryotes?
Biology Direct, 2006 Martin & Koonin recently proposed that the eukaryote nucleus evolved as a quality control mechanism to prevent ribosome readthrough into introns. In their scenario, the bacterial ancestor of mitochondria was resident in an archaeal cell, and group II ...
Poole Anthony M
doaj +1 more source
Group II introns break new boundaries: presence in a bilaterian's genome. [PDF]
PLoS ONE, 2008 Group II introns are ribozymes, removing themselves from their primary transcripts, as well as mobile genetic elements, transposing via an RNA intermediate, and are thought to be the ancestors of spliceosomal introns. Although common in bacteria and most
Yvonne Vallès +2 more
doaj +1 more source