Results 81 to 90 of about 15,121,811 (367)

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

Singular matrices possessing the triangle property

open access: yesSpecial Matrices
It is known that the inverse of an invertible real square matrix satisfying the triangle property is a tridiagonal matrix. In this note, results that may be considered as analogues of this assertion are obtained for the Moore-Penrose inverse and the ...
Priya K. Kranthi, Sivakumar K. C.
doaj   +1 more source

The perturbation of the group inverse under the stable perturbation in a unital ring [PDF]

open access: yes, 2012
Let $\R $ be a ring with unit 1 and $a\in \R, \bar{a}=a+\delta a\in \R $ such that $a^#$ exists. In this paper, we mainly investigate the perturbation of the group inverse $a^#$ on $\R$.
Fapeng Du, Yifeng Xue
semanticscholar   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Inverse renormalization group based on image super-resolution using deep convolutional networks

open access: yesScientific Reports, 2021
The inverse renormalization group is studied based on the image super-resolution using the deep convolutional neural networks. We consider the improved correlation configuration instead of spin configuration for the spin models, such as the two ...
Kenta Shiina   +4 more
doaj   +1 more source

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

open access: yesFEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp   +13 more
wiley   +1 more source

Further results on the group inverse of some anti-triangular block matrices

open access: yes, 2014
Suppose ℜ is a right Ore domain with unity 1. In this paper, we investigate the existence of the group inverse of some anti-triangular block matrices over ℜ and obtain the sufficient and necessary conditions for such existence.
C. Cao, Hanyu Zhang, Y. Ge
semanticscholar   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

open access: yesFEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies   +3 more
wiley   +1 more source

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