Results 181 to 190 of about 708,548 (296)

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Editorial: System dynamics modeling in public health: implementations and implications

open access: yesFrontiers in Public Health
Kimberly Jinnett   +4 more
doaj   +1 more source

Application of systems dynamics and group model building to identify barriers and facilitators to acute care delivery in a resource limited setting. [PDF]

open access: yesBMC Health Serv Res, 2021
Muttalib F   +8 more
europepmc   +1 more source

A comparison of the UK Standard Assessment Procedure (SAP) and detailed simulation of building-integrated renewable energy systems

open access: yes, 2009
The drive to reduce UK Carbon Emissions directly associated with dwellings and to achieve a zero carbon home dictates that Renewable Energy Technologies will have an increasingly large role in the built environment.
Anderson, B. R.   +6 more
core  

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

Using Group Model Building to Capture the Complex Dynamics of Scaling Up District-Level Surgery in Arusha Region, Tanzania. [PDF]

open access: yesInt J Health Policy Manag, 2022
Broekhuizen H   +11 more
europepmc   +1 more source

Group Model Building: A Systematic Review of the Literature

open access: yesTurk Turizm Arastirmalari Dergisi, 2021
Ali Haji Gholam Saryazdi   +3 more
openaire   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel   +4 more
wiley   +1 more source

Applying system dynamics methods for local obesity prevention: results from a group model building study in Amsterdam, the Netherlands. [PDF]

open access: yesHealth Res Policy Syst
Waterlander W   +9 more
europepmc   +1 more source

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