Results 51 to 60 of about 64,923 (310)
Purpose: The aim of this paper is to present the regulatory obligations imposed by the President of the Office of Electronic Communications (hereafter: President of UKE) on telecom enterprises with significant market power in the retail and wholesale ...
Ewa M. Kwiatkowska, Iwona Cieślak
doaj
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
An obligate intermediate along the slow folding pathway of a group II intron ribozyme [PDF]
Most RNA molecules collapse rapidly and reach the native state through a pathway that contains numerous traps and unproductive intermediates. The D135 group II intron ribozyme is unusual in that it can fold slowly and directly to the native state, despite its large size and structural complexity. Here we use hydroxyl radical footprinting and native gel
Su, Linhui Julie +2 more
openaire +2 more sources
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
The paper analyses the legal definition of railway areas in Poland based on the Railway Transport Act. The author tries to find an answer to the question of what the legal status of railway areas in the Polish legal system is, with emphasis on the ...
Piotr Szulc
doaj +1 more source
The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Thai Law Enforcement of Obligations under the ASEAN Agreements on Environment
This research aims to study historical development and basic principles of obligations under the ASEAN agreements on environment in the ASEAN Social and Cultural Community (ASCC) and the measures of Thai law enforcement to comply with the obligations of ...
สุรพล ศรีวิทยา
doaj +1 more source
An Islamic Framework for Employer-Employee Relationships
Introduction Islamic teachings envisage a balanced society achieved through the functioning of Islamic institutions. This paper visualizes three main institutions: ukhiwah, ‘adl, and ihsan.
M. Ramzan Akhtar
doaj +1 more source
Kin selection, not group augmentation, predicts helping in an obligate cooperatively breeding bird [PDF]
Kin selection theory has been the central model for understanding the evolution of cooperative breeding, where non-breeders help bear the cost of rearing young. Recently, the dominance of this idea has been questioned; particularly in obligate cooperative breeders where breeding without help is uncommon and seldom successful.
L E, Browning +4 more
openaire +2 more sources

