Results 61 to 70 of about 167,375,017 (300)

Idursulfase pharmacokinetics, cellular uptake, and pharmacodynamics: Effect of sialylation and manufacturing process

Engineering Reports, 2020
Recombinant iduronate‐2‐sulfatase (idursulfase) is available for the treatment of mucopolysaccharidosis II (MPS II). The effectiveness of this glycoprotein may depend on post‐translational modifications such as glycosylation and sialylation during ...
Antony R. Garcia, Justin Lamsa, David A. H. Whiteman, Joseph Muenzer   +3 more
doaj   +1 more source

Antea Group Archeologie 2017/21

, 2017
In januari 2017 heeft Antea Group, in opdracht van Alliander N.V., een inventariserend veldonderzoek door middel van verkennende boringen uitgevoerd ten behoeve van een plangebied langs de zuidberm van de A15 tussen Ochten en Dodewaard in de gemeente ...
Teekens, Drs. P.C. (Antea group)
core   +1 more source

Self‐Regulated Learning Meets AI: Reinterpreting Self‐Regulation, Co‐Regulation, and Socially Shared Regulation in Human–AI Interaction

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Advancing artificial intelligence (AI) has transformed learning and work, yet higher education and professional development programs have not systematically equipped learners for AI‐prevalent environments. This lack of preparation creates uncertainty regarding control, responsibility, trust, and accountability.
Moon‐Heum Cho, Jerusalem Merkebu
wiley   +1 more source

Development of a Triton X‐100 replacement for effective virus inactivation in biotechnology processes

Engineering Reports, 2019
After the transmission of human viruses through plasma derivatives had been recognized in the early 1980s, virus inactivation and then removal steps have been implemented into their manufacturing processes.
Jean‐Baptiste Farcet, Johanna Kindermann, Michael Karbiener, Thomas R. Kreil   +3 more
doaj   +1 more source

Antea Group Archeologie 2015/69

, 2017
In opdracht van de gemeente Valkenswaard heeft Antea Group in mei en juni 2015 een archeologisch bureauonderzoek uitgevoerd. Dit in het kader van een bestemmingsplanwijziging van het terrein ter hoogte van de Pastoor Heerkensdreef 29 in Valkenswaard.
Sophie, G. (Antea Group)
core   +1 more source

Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants

Annals of Clinical and Translational Neurology, EarlyView.
Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants. ABSTRACT Objective Return of disease activity is expected when patients discontinue disease‐modifying therapy (DMT) for multiple sclerosis (MS). Some MS DMTs are associated with higher‐than‐expected disease activity (rebound) after discontinuation.
Ralf Gold, Krzysztof W. Selmaj, Regina Berkovich, Jeffrey A. Cohen, Giancarlo Comi, Eva K. Havrdová, James K. Sheffield, Hetal Desai, Chun‐Yen Cheng, Jon V. Riolo, Andrew Thorpe, Erik DeBoer, Bruce A. C. Cree   +12 more
wiley   +1 more source

Assessing the impact on caregivers caring for patients with rare pediatric lysosomal storage diseases: development of the Caregiver Impact Questionnaire

Journal of Patient-Reported Outcomes, 2019
Background Capturing the impact of caring for patients with debilitating rare disease is important for understanding disease burden. We aimed to develop and validate an instrument to measure the impact on caregivers of caring for children with three ...
Magdalena Harrington, Asha Hareendran, Anne Skalicky, Hilary Wilson, Marci Clark, Jaromir Mikl   +5 more
doaj   +1 more source

GAD65 Antibody ELISA With Extended Reportable Range: Validation and Guidance for Neurological Practice

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To (1) validate GAD65‐ELISA detection and quantification for type 1 diabetes mellitus and autoimmune neurological diagnoses, (2) correlate ELISA results (reference range < 5 IU/mL) with established radioimmunoprecipitation assay (RIA; ≤ 0.02 nmol/L), and (3) define ELISA clinical utility and pitfalls.
Andrew McKeon, Dana Olofson, Diana Anissian, Divyanshu Dubey, Eoin P. Flanagan, Max C. Herman, Sarosh R. Irani, Daniel H. Lachance, Maria A. Willrich, Sean Pittock, John R. Mills, Anastasia Zekeridou   +11 more
wiley   +1 more source

Foreign capital as a determinant of the non-financial reporting development in insurance companies of the Visegrad Group countries [PDF]

, 2021
Insurance companies are institutions of public trust, and this affects their corporate culture, strategies and management systems. One of the image concerns is reporting on socially responsible actions in non-financial reports. The prime objective of the
Jarolímová, Blanka, Lament, Marzanna
core   +1 more source

Alirokumab in the practice of a multidisciplinary outpatient hospital: results of an open, noncomparative prospective study

Сеченовский вестник, 2020
Aim. Evaluation of efficacy and safety of alirocumab in patients with atherogenic dyslipidemia in real clinical practice.Materials and methods. Patients with atherogenic dyslipidemia and failure to achieve target lipid levels were included in a ...
A. O. Bueverov, P. O. Bogomolov, A. A. Kucherov, V. E. Syutkin   +3 more
doaj   +1 more source