Results 61 to 70 of about 174,489,474 (248)

Assessing the impact on caregivers caring for patients with rare pediatric lysosomal storage diseases: development of the Caregiver Impact Questionnaire

Journal of Patient-Reported Outcomes, 2019
Background Capturing the impact of caring for patients with debilitating rare disease is important for understanding disease burden. We aimed to develop and validate an instrument to measure the impact on caregivers of caring for children with three ...
Magdalena Harrington, Asha Hareendran, Anne Skalicky, Hilary Wilson, Marci Clark, Jaromir Mikl   +5 more
doaj   +1 more source

Nationwide Survey of Association Between Fever and Epileptic Seizure in CDKL5 Deficiency Disorder Revealed Therapeutic Implications

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective CDKL5 deficiency disorder (CDD) is a rare, severe developmental and epileptic encephalopathy. There is a pressing need to develop effective and sustainable therapeutic strategies. We aimed to investigate the causal association between febrile episodes and epileptic seizures for therapeutic implications in CDD patients.
Siyi Wang, Jialin Du, Jinghui Liu, Dongmei Hu, Hongxin Wang, Xiaoxiao Man, Lehong Gao, Shimin Hu, Xianghong Meng, Hongyang Zhao, Minjing Hu, Yingxue Yang, Zhiqi Xiong, Liankun Ren   +13 more
wiley   +1 more source

Prognostic parameters affecting the effectiveness of removing benign epithelial neoplasms of the LST type in the colon and rectum

Acta Biomedica Scientifica
Background. It is an undeniable fact that colon polyps are associated with colorectal cancer. The main measure for preventing colorectal cancer is the removal of epithelial neoplasms. However, the effectiveness of resection depends on various factors.Aim.
A. A. Arkhipova, V. V. Anishchenko, D. Kh. Abakarova   +2 more
doaj   +1 more source

Alirokumab in the practice of a multidisciplinary outpatient hospital: results of an open, noncomparative prospective study

Сеченовский вестник, 2020
Aim. Evaluation of efficacy and safety of alirocumab in patients with atherogenic dyslipidemia in real clinical practice.Materials and methods. Patients with atherogenic dyslipidemia and failure to achieve target lipid levels were included in a ...
A. O. Bueverov, P. O. Bogomolov, A. A. Kucherov, V. E. Syutkin   +3 more
doaj   +1 more source

Subjective Cognitive Concerns and Cognitive Trajectories in Parkinson's Disease: Biomarker Impact

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the relationship of subjective cognitive concerns (SCC) with biomarkers of Alzheimer's disease (AD), neurodegeneration, and Parkinson's disease (PD) and domain‐specific cognitive trajectories among cognitively unimpaired persons with de novo PD. Method Cognitively unimpaired participants with SCC (n = 294) and without SCC (
Francesca V. Lopez, Fareshte Erani, Katherine J. Bangen, David G. Coughlin, Douglas Galasko, Kelsey R. Thomas   +5 more
wiley   +1 more source

The Sit Listen and Laugh Tour

, 2013
ColourKirby Group of Companies, Trent ...

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Probabilistic Justification of the Values of Reliability Factors for the Design of Buildings and Structures Made of Large Reinforced Concrete Modules

Железобетонные конструкции
The article presents a justification of the values for refined safety factors used in the design of buildings and structures made of large reinforced concrete modules.
S. A. Ambartsumyan, A. V. Manukyan, O. V. Mkrtychev   +2 more
doaj   +1 more source

A Two‐Stage Plasma Biomarker Algorithm Reduces Amyloid PET Use and the p‐Tau217 Gray Zone

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma p‐Tau217 leaves 30%–50% of patients in an indeterminate “gray zone” often requiring Aβ‐PET. We developed GRAD (Gatekeeper‐Reflex for Alzheimer's Disease), a two‐stage Aβ‐positivity prediction model to improve classification while reserving Aβ‐PET for residual uncertainty.
Harthik Parankusham, Casey Vanderlip, Colin Birkenbihl, Eashwar Krishna, Chizobam Ugboaja, Andrew E. Budson, Brandon Frank, for the Alzheimer's Disease Neuroimaging Initiative   +7 more
wiley   +1 more source

International and EC Tax Aspects of Group of Companies. Spain

, 2008
PART I: GENERAL INTRODUCTION ON COMPANY LAW ON GROUPS. 1.1. Definition of “group” up to 31 December 2007. 1.2. Definition of “group” as of 1 January 2008. 1.3. Effects of group status under Company Law. 1.4.
Cencerrado Millán, Emilio
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THE STUDY VULNERABILITY OF INDONESIAN COMPANIES, APPLYING ALTMAN MODEL TO BOTH THE BANKRUPT GROUP OF COMPANIES AND THE SURVIVING GROUP OF COMPANIES [PDF]

, 2010
THE STUDY VULNERABILITY OF INDONESIAN COMPANIES, APPLYING ALTMAN MODEL TO BOTH THE BANKRUPT GROUP OF COMPANIES AND THE SURVIVING GROUP OF COMPANIES - Altman Z score, predicting bankruptcy, financial distress, Z score ...
YUNITA, FELICIA
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