Results 41 to 50 of about 174,489,474 (248)

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source

About approaches to a universal distributed trusted registry to ensure confidentiality of system information

Безопасность информационных технологий, 2019
Currently, under the current international sanctions, the task of building a system of distributed registries with high transactional speed and using symmetric cryptographic algorithms, as well as providing minimal or controlled disclosure of data about ...
Natalya I. Kasperskaya, Vasily V. Kuzmenko, Rustem N. Khairetdinov, Andrey Yu. Shcherbakov   +3 more
doaj   +1 more source

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

Molecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir, Elena Haro‐Martínez, Sandra Blasco‐Benito, Chiara Cannatà, José Ángel Palomeque, Anna López‐Plana, Maria Sanz‐Flores, Marc Sabartés, Cristina Fornaguera, Toni Celià‐Terrassa   +9 more
wiley   +1 more source

Reflection of documents in the digital twin of the company and calculation of their impact on human behavior in the simulation model

E-Management, 2021
The formation and formation of the Industry 4.0 concept stimulated the discussion of the use of computer technology in various areas of economic activity and, in particular, in the automation of social systems management.
M. V. Samosudov
doaj   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

Antea Group Archeologie 2020/204

, 2020
N.B.: Het onderzoek is voorgelegd aan en beoordeeld door de bevoegde overheid. Deze heeft het onderstaande advies overgenomen. Antea Group heeft in oktober 2020 een inventariserend veldonderzoek door middel van boringen (verkennende fase) uitgevoerd in ...
Fens, R. (Antea Group), Fleuren, I. (Antea Group), I. Fleuren, R. Fens   +3 more
core   +1 more source

Using cell‐free RNA to identify B‐ and T‐cell clonality for diagnosis and monitoring of B‐ and T‐cell neoplasms

FEBS Open Bio, EarlyView.
Using peripheral blood for determining B‐cell or T‐cell clonality is more reliable when we use cell‐free RNA (cfRNA) because cells release blood significantly more RNA than DNA. Next‐generation sequencing (NGS) of cfRNA allows us to evaluate fragment cfRNA and evaluate clonality reliably without the need for prior determination of the specific dominant
Adam Albitar, Sally Agersborg, Ahmed Charifa, Pooja Phull, Noa Biran, David Vesole, Harsh Parmar, Andrew Pecora, Andrew Ip, Andre Goy, David Siegel, Maher Albitar   +11 more
wiley   +1 more source

YESTERDAY AND TODAY THE CENTER OF LABORATORY REFERENCE MATERIALS LTD «ECOHIM»

Стандартные образцы, 2017
The article describes the experience of the development and production of certified reference materials intended for metrological maintenance of ecological and analytical measurement and control oil product quality.
V. O. Arapov, D. A. Pashnin, N. G. Kovaleva   +2 more
doaj  

Self‐Regulated Learning Meets AI: Reinterpreting Self‐Regulation, Co‐Regulation, and Socially Shared Regulation in Human–AI Interaction

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Advancing artificial intelligence (AI) has transformed learning and work, yet higher education and professional development programs have not systematically equipped learners for AI‐prevalent environments. This lack of preparation creates uncertainty regarding control, responsibility, trust, and accountability.
Moon‐Heum Cho, Jerusalem Merkebu
wiley   +1 more source

Globaldev Group IT company

, 2023
Why Global Software Development Partners Are Reshaping the IT Landscape In a world where digital transformation is no longer optional, companies of all sizes are turning to global software development partners to accelerate innovation, reduce costs, and build scalable tech solutions.
openaire   +3 more sources