Results 61 to 70 of about 1,597,900 (327)

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Balanced Tripartite Entanglement, the Alternating Group A4 and the Lie Algebra $sl(3,C) \oplus u(1)$

, 2009
We discuss three important classes of three-qubit entangled states and their encoding into quantum gates, finite groups and Lie algebras. States of the GHZ and W-type correspond to pure tripartite and bipartite entanglement, respectively.
Acin, Bosma, Brif, Cahn, Carruthers, Choudhary, Coffman, Coffman, Duff, Dömötor, Dür, Frappat, Frappat, Hall, Helgason, Hornos, Kibler, Kibler, Korbicz, Lévay, Lévay, Ma, Ma, Metod Saniga, Michel Planat, Planat, Planat, Planat, Planat, Planat, Péter Lévay, Vourdas, Yang   +32 more
core   +4 more sources

A (3+1)-dimensional generalized BKP-Boussinesq equation: Lie group approach

Results in Physics, 2019
A (3+1)-D generalized B-type KP-Boussinesq equation, which was recently formulated in the literature, is investigated here from Lie group standpoint. A solution is obtained by Lie symmetry reductions and direct integration in terms of incomplete elliptic
Chaudry Masood Khalique, Letlhogonolo Daddy Moleleki   +1 more
doaj   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

About Periodic Shunkov Group Saturated with Finite Simple Groups of Lie Type Rank 1

Известия Иркутского государственного университета: Серия "Математика", 2016
The property of group G to be saturated with given set of groups X is a natural generalization of locally-cover definition (in class of locally finite groups) on periodic groups. Locally-finite group, witch has a locally-cover contains from finite simple
A. Shlepkin
doaj  

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

Automophisms of Nil-Triangular Subrings of Algebras Chevalley Type $G_2$ Over Integral Domain. I

Известия Иркутского государственного университета: Серия "Математика"
Let $N\Phi(K)$ be the nil-triangular subalgebra of the Chevalley algebra over an associative commutative ring $K$ with the identity associated with a root system $\Phi$.
A. V. Kazakova
doaj   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

A Lie group variational integrator in a closed-loop vector space without a multiplier [PDF]

Mechanical Sciences
As a non-tree multi-body system, the dynamics model of four-bar mechanism is a differential algebraic equation. The constraints breach problem leads to many problems for computation accuracy and efficiency.
L. Bai, L. Xia, X. Ge
doaj   +1 more source

Recognition of finite exceptional groups of Lie type [PDF]

Transactions of the American Mathematical Society, 2015
Let $q$ be a prime power and let $G$ be an absolutely irreducible subgroup of $GL_d(F)$, where $F$ is a finite field of the same characteristic as $\F_q$, the field of $q$ elements. Assume that $G \cong G(q)$, a quasisimple group of exceptional Lie type over $\F_q$ which is neither a Suzuki nor a Ree group.
Liebeck, MW, O'Brien, EA
openaire   +5 more sources