Results 61 to 70 of about 199,468 (335)

In vivo evidence for glycyl radical insertion into a catalytically inactive variant of pyruvate formate‐lyase

open access: yesFEBS Letters, EarlyView.
Dimeric pyruvate formate‐lyase cleaves pyruvate using a radical‐based mechanism. G734 serves as a radical storage location, and the radical is transferred to the catalytic C419 residue. Mutation of the C418‐C419 pair causes loss of enzyme activity, but does not impede radical introduction onto G734. Therefore, cis‐ but not trans‐radical transfer occurs
Michelle Kammel   +2 more
wiley   +1 more source

Evolutionary interplay between viruses and R‐loops

open access: yesFEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi   +4 more
wiley   +1 more source

Isometries in finite groups of Lie type

open access: yesJournal of Algebra, 1973
Publisher Summary This chapter discusses the isometries in finite groups of lie type. Let G be a connected semisimple linear algebraic group and σ a surjective endomorphism of G, such that the group of fixed points G σ = G is finite. Then G is a finite group of Lie type. Let T be a maximal torus of G fixed by σ and T = T, H = N G (T), H/T = W. Then T
openaire   +3 more sources

Single‐cell insights into the role of T cells in B‐cell malignancies

open access: yesFEBS Letters, EarlyView.
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley   +1 more source

Unipotent subgroups of groups of Lie type

open access: yesJournal of Algebra, 1983
Let G = G’ be either a simple algebraic group over an algebraically closed field k or a finite Chevalley group (normal or twisted) over k = F, with q > 4. For the case of an algebraic group all groups discussed are taken to be closed subgroups of G. In this paper we prove results that parallel those in [ 141, where we deterined those subgroups of G ...
openaire   +3 more sources

Lie-type-like groups

open access: yesJournal of Algebra, 2016
Abstract A finite simple group of Lie type in defining characteristic p has exactly two p-blocks, the principal block and a block of defect zero consisting of the Steinberg character whose degree is the p-part of the order of the group. In this paper we characterize finite groups G which have exactly the principal p-block and a p-block of defect zero
Yanjun Liu   +2 more
openaire   +2 more sources

Matrix Generators for Exceptional Groups of Lie Type [PDF]

open access: yesJournal of Symbolic Computation, 2001
The authors give a uniform method of constructing generators for matrix representations of finite groups of Lie type with particular emphasis on the exceptional groups. The algorithm constructs matrices for the action of root elements on the lowest dimension representation of an associated Lie algebra.
Howlett, Robert J.   +2 more
openaire   +3 more sources

Cyclic nucleotide signaling as a drug target in retinitis pigmentosa

open access: yesFEBS Letters, EarlyView.
Disruptions in cGMP and cAMP signaling can contribute to retinal dysfunction and photoreceptor loss in retinitis pigmentosa. This perspective examines the mechanisms and evaluates emerging evidence on targeting these pathways as a potential therapeutic strategy to slow or prevent retinal degeneration.
Katri Vainionpää   +2 more
wiley   +1 more source

Elderly Gravida with Bombay Blood Group and Placenta Previa Managed with Autologous Blood Transfusion

open access: yesCase Reports in Obstetrics and Gynecology, 2020
The Bombay blood group is a rare blood type with an incidence of around one in a million. There is no known reported case of an obstetric patient with the Bombay blood group from Nepal.
Pooja Paudyal   +4 more
doaj   +1 more source

Combinatorial Hopf algebra of supercharacters of type D [PDF]

open access: yesDiscrete Mathematics & Theoretical Computer Science, 2012
We provide a Hopf algebra structure on the supercharacter theory for the unipotent upper triangular group of type {D} over a finite field. Also, we make further comments with respect to types {B} and {C}. Type {A} was explored by M. Aguiar et. al (2010),
Carolina Benedetti
doaj   +1 more source

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