Results 61 to 70 of about 199,468 (335)
Dimeric pyruvate formate‐lyase cleaves pyruvate using a radical‐based mechanism. G734 serves as a radical storage location, and the radical is transferred to the catalytic C419 residue. Mutation of the C418‐C419 pair causes loss of enzyme activity, but does not impede radical introduction onto G734. Therefore, cis‐ but not trans‐radical transfer occurs
Michelle Kammel+2 more
wiley +1 more source
Evolutionary interplay between viruses and R‐loops
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi+4 more
wiley +1 more source
Isometries in finite groups of Lie type
Publisher Summary This chapter discusses the isometries in finite groups of lie type. Let G be a connected semisimple linear algebraic group and σ a surjective endomorphism of G, such that the group of fixed points G σ = G is finite. Then G is a finite group of Lie type. Let T be a maximal torus of G fixed by σ and T = T, H = N G (T), H/T = W. Then T
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Single‐cell insights into the role of T cells in B‐cell malignancies
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley +1 more source
Unipotent subgroups of groups of Lie type
Let G = G’ be either a simple algebraic group over an algebraically closed field k or a finite Chevalley group (normal or twisted) over k = F, with q > 4. For the case of an algebraic group all groups discussed are taken to be closed subgroups of G. In this paper we prove results that parallel those in [ 141, where we deterined those subgroups of G ...
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Abstract A finite simple group of Lie type in defining characteristic p has exactly two p-blocks, the principal block and a block of defect zero consisting of the Steinberg character whose degree is the p-part of the order of the group. In this paper we characterize finite groups G which have exactly the principal p-block and a p-block of defect zero
Yanjun Liu+2 more
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Matrix Generators for Exceptional Groups of Lie Type [PDF]
The authors give a uniform method of constructing generators for matrix representations of finite groups of Lie type with particular emphasis on the exceptional groups. The algorithm constructs matrices for the action of root elements on the lowest dimension representation of an associated Lie algebra.
Howlett, Robert J.+2 more
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Cyclic nucleotide signaling as a drug target in retinitis pigmentosa
Disruptions in cGMP and cAMP signaling can contribute to retinal dysfunction and photoreceptor loss in retinitis pigmentosa. This perspective examines the mechanisms and evaluates emerging evidence on targeting these pathways as a potential therapeutic strategy to slow or prevent retinal degeneration.
Katri Vainionpää+2 more
wiley +1 more source
The Bombay blood group is a rare blood type with an incidence of around one in a million. There is no known reported case of an obstetric patient with the Bombay blood group from Nepal.
Pooja Paudyal+4 more
doaj +1 more source
Combinatorial Hopf algebra of supercharacters of type D [PDF]
We provide a Hopf algebra structure on the supercharacter theory for the unipotent upper triangular group of type {D} over a finite field. Also, we make further comments with respect to types {B} and {C}. Type {A} was explored by M. Aguiar et. al (2010),
Carolina Benedetti
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