Results 71 to 80 of about 1,597,900 (327)
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Additive polynomials for finite groups of Lie type [PDF]
Israel Journal of Mathematics, 2011 This paper provides a realization of all classical and most exceptional finite groups of Lie type as Galois groups over function fields over F_q and derives explicit additive polynomials for the extensions. Our unified approach is based on results of Matzat which give bounds for Galois groups of Frobenius modules and uses the structure and ...
Albert, Maximilian, Maier, Annette
openaire +2 more sources
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
The Cauchy Problem for Darboux Integrable Systems and Non-Linear d'Alembert Formulas
Symmetry, Integrability and Geometry: Methods and Applications, 2013 To every Darboux integrable system there is an associated Lie group G which is a fundamental invariant of the system and which we call the Vessiot group.
Mark E. Fels, Ian M. Anderson
doaj +1 more source
Vacuum polarization of scalar field on Lie groups with Bi-invariant metric [PDF]
Компьютерные исследования и моделирование, 2015 We consider vacuum polarization of a scalar field on the Lie groups with a bi-invariant metric of Robertson-Walker type. Using the method of orbits we found expression for the vacuum expectation values of the energy-momentum tensor of the scalar field ...
Alexander Igorevich Breev +1 more
doaj +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Reduction of Dynamics with Lie Group Analysis
Advances in Mathematical Physics, 2012 This paper is mainly a review concerning singular perturbation methods by means of Lie group analysis which has been presented by the author. We make use of a particular type of approximate Lie symmetries in those methods in order to construct reduced ...
M. Iwasa
doaj +1 more source
Lp - Liouville theorems for invariant evolution equations
Bruno Pini Mathematical Analysis Seminar, 2014 Some Liouville-type theorems in Lebesgue spaces for several classes of evolution equations are presented. The involved operators are left invariant with respect to Lie group composition laws. Results for both solutions and sub-solutions are given.
Alessia E. Kogoj
doaj +1 more source
Overview of molecular signatures of senescence and associated resources: pros and cons
FEBS Open Bio, EarlyView.Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source
The essential $l$-dimension of finite groups of Lie type, $l \neq 2$ [PDF]
, 2022 Hannah Knight
openalex +1 more source