Results 71 to 80 of about 199,468 (335)
FEBS Letters, EarlyView.Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria +3 more
wiley +1 more source
Groups with a central factor of Lie type
Journal of Algebra, 2002 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +2 more sources
From omics to AI—mapping the pathogenic pathways in type 2 diabetes
FEBS Letters, EarlyView.Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan +2 more
wiley +1 more source
Molecular Oncology, EarlyView.Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley +1 more source
Molecular Oncology, EarlyView.This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti +10 more
wiley +1 more source
Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma
Molecular Oncology, EarlyView.The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias +12 more
wiley +1 more source
About Periodic Shunkov Group Saturated with Finite Simple Groups of Lie Type Rank 1
Известия Иркутского государственного университета: Серия "Математика", 2016 The property of group G to be saturated with given set of groups X is a natural generalization of locally-cover definition (in class of locally finite groups) on periodic groups. Locally-finite group, witch has a locally-cover contains from finite simple
A. Shlepkin
doaj
Alternating subgroups of exceptional groups of Lie type [PDF]
, 2015 In this paper, we examine embeddings of alternating and symmetric groups into almost simple groups of exceptional type. In particular, we prove that if the alternating or symmetric group has degree equal to 5, or 8 or more, then it cannot appear as the ...
David A. Craven
semanticscholar +1 more source
Chains of Subgroups in Groups of Lie Type III
Journal of the London Mathematical Society, 1990 The authors continue their study of the maximal length \(\ell(G)\) of a chain of subgroups \(G=G_ 0>G_ 1>\dots>G_ k=1\) in a finite simple group of Lie type in characteristic \(p\). In the first paper of the series [J. Algebra 132, No. 1, 174-184 (1990; Zbl 0714.20011)] they gave a precise formula in the case \(p=2\).
Alexandre Turull, Ron Solomon
openaire +4 more sources
Molecular Oncology, EarlyView.Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source