Results 131 to 140 of about 1,083,386 (308)

Responsibility for group transgressions

, 2010
Thesis (Ph.D.)--Georgetown University, 2010.; Includes bibliographical references.; Text (Electronic thesis) in PDF format. This dissertation seeks to develop a novel account of the responsibility members of a group bear for transgressions in
Sepinwall, Amy.
core  

Consumer ethics, religiosity, and consumer social responsibility: are they related?

, 2018
Purpose: In the past few years, companies have made significant contributions towards Corporate Social Responsibilities (CSR) as a strategy to improve business image.
Denni I. Arli, Tjiptono, Fandy, Arli, Denni, Fandy Tjiptono   +3 more
core   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

The moral status of the corporation, collective responsibility, and the distribution of blame

The moral status of the corporation is a foundational issue in business ethics. A long-running debate has considered whether a corporation can be considered a moral agent in its own right, akin to an individual human agent. As Moore (1999, p.
Cowton, Christopher J.
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Role and contribution of the non-executive director : implications for corporate social responsibility in the boardroom [PDF]

, 2005
This research examines the role and contribution of the Non Executive Director (NED) within the corporate board. The literature identifies the NED as a boundary spanner.
Barratt, Ruth
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Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Group Responsibility and Historicism [PDF]

In this paper, we focus on the moral responsibility of organized groups in light of historicism. Historicism is the view that any morally responsible agent must satisfy certain historical conditions, such as not having been manipulated.
de Haan, Niels, Collins, Stephanie
core   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Cultural perspectives on the meaning of corporate social responsibility in a third sector organisation

How can Corporate Social Responsibility best be understood, what is its range of application and what insights can culture provide when considering the responsibilities of a third sector organisation?
Hussein, Rima
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Corporate social responsibility: A strategy for sustainable business success. An analysis of 20 selected British companies

, 2010
Purpose – This paper attempts to prove that strategically investing in corporate social responsibility (CSR) will maximize profits while satisfying the demands from multiple stakeholders.
Godwin Odemilin, Martin Samy, Bampton, R, Odemilin, G, Roberta Bampton, Samy, M   +5 more
core   +1 more source