Results 141 to 150 of about 3,506,344 (312)

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

FEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde, Unai Alduntzin, Gorka Prieto, Ugo Mayor   +3 more
wiley   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

Cultivating physical literacy and prosocial behavior through basketball: a quasi-experimental study on the Teaching Personal and Social Responsibility (TPSR) model

BMC Public Health
Background Physical literacy and social responsibility are crucial educational outcomes that foster lifelong physical activity and prosocial behaviors. The Teaching Personal and Social Responsibility (TPSR) model, which is widely applied to cultivate a ...
Bin Xie, Siman Lei, Yiren Wu, Infong Chang, Mengyun Zhao, Fangyuan Ju   +5 more
doaj   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

FEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman, Katarzyna Stapor, Leszek Konieczny, Krzysztof Gądek, Piotr Nowakowski   +4 more
wiley   +1 more source

\u27The Inferior Parts of the Body\u27: The Development and Role of Women\u27s Meetings in the Early Quaker Movement

, 2014
This article is a study of the development and role of early Quaker women\u27s Meetings during the second half of the seventeenth century. It is based upon the contemporary records of the Owstwick women\u27s Monthly Meeting, held in the East Riding of ...
Shaw, Gareth
core  

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

A responsible authorship culture is needed and it is a collective responsibility. [PDF]

PLoS Med
Kiermer V, Bibbins-Domingo K, Skipper M.
europepmc   +2 more sources

Who is Responsible for Particulate Matter in South Korea’s Atmosphere? The Role of Social Media and Attribution of Responsibility on Risk Perception and Protective Behaviors

International Journal of Communication
This study analyzed national survey data from South Korean respondents to examine how social media use influences the attribution of responsibility to an out-group or in-group, risk perceptions, and protective behavioral intentions about particulate ...
Doo-Hun Choi
doaj  

Playing with the Good Guys - A Public Good Game with Endogenous Group Formation [PDF]

In public good games, voluntary contributions tend to start off high and decline as the game is repeated. If high contributors are matched, however, contributions tend to stay high.
Jo Thori Lind, Karen Evelyn Hauge, Karine Nyborg, Kjell Arne Brekke   +3 more
core